Prevention and Management of Cataracts in Children with Juvenile Idiopathic Arthritis-associated Uveitis

Overview

Journal Curr Rheumatol Rep

Publisher Current Science

Specialty Rheumatology

Date 2011 Dec 28

PMID 22201032

Citations 16

Authors

Sheila Angeles-Han

Steven Yeh

Affiliations

Soon will be listed here.

Abstract

Juvenile idiopathic arthritis (JIA)-associated uveitis can be associated with vision-compromising complications such as cataracts, glaucoma, synechiae, and band keratopathy. Of these, cataracts are one of the most common sequelae of JIA-associated uveitis and can result in significant visual disability. Risk factors for cataracts include posterior synechiae and longstanding ocular inflammation. Prevention of cataract development is crucial through appropriate control of uveitis. However, not all preventive measures are successful, and further management consisting of medical and surgical techniques is often necessary. Various factors should be taken into consideration when deciding on cataract management, including timing of surgery and placement of an intraocular lens. Continued partnership between pediatric rheumatologists and pediatric ophthalmologists can help ensure favorable visual outcomes.

Citing Articles

A clearer vision: insights into juvenile idiopathic arthritis-associated uveitis.

M Bani Khalaf I, Jain H, Vora N, Ain N, Murtaza F, Ram M Proc (Bayl Univ Med Cent). 2024; 37(2):303-311.

PMID: 38343470 PMC: 10857453. DOI: 10.1080/08998280.2024.2305567.

Evolution and trends of childhood cataract research in the past 10 years: A scientometric analysis.

Tan Y, Chen H, Gong S, Zou Y, Shen Y, Luo L Heliyon. 2023; 9(6):e17590.

PMID: 37416629 PMC: 10320269. DOI: 10.1016/j.heliyon.2023.e17590.

Outcome of cataract surgery in pediatric uveitis (experience at King Khalid Eye Specialist Hospital).

AlAmeer A, Al Shamrani M Oman J Ophthalmol. 2022; 15(1):43-48.

PMID: 35388246 PMC: 8979397. DOI: 10.4103/ojo.ojo_15_21.

Trends of Multimorbidity Patterns over 16 Years in Older Taiwanese People and Their Relationship to Mortality.

Ho H, Yeh C, Cheng-Chung Wei J, Chu W, Lee M Int J Environ Res Public Health. 2022; 19(6).

PMID: 35329003 PMC: 8950835. DOI: 10.3390/ijerph19063317.

Cataract Surgery with Intraocular Lens Implantation in Juvenile Idiopathic Arthritis-Associated Uveitis: Outcomes in the Era of Biological Therapy.

Bolletta E, Coassin M, Iannetta D, Mastrofilippo V, Aldigeri R, Invernizzi A J Clin Med. 2021; 10(11).

PMID: 34072679 PMC: 8198606. DOI: 10.3390/jcm10112437.

References

Sen H, Levy-Clarke G, Faia L, Li Z, Yeh S, Barron K . High-dose daclizumab for the treatment of juvenile idiopathic arthritis-associated active anterior uveitis. Am J Ophthalmol. 2009; 148(5):696-703.e1. PMC: 2922905. DOI: 10.1016/j.ajo.2009.06.003. View

Heiligenhaus A, Niewerth M, Ganser G, Heinz C, Minden K . Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines. Rheumatology (Oxford). 2007; 46(6):1015-9. DOI: 10.1093/rheumatology/kem053. View

Skarin A, Elborgh R, Edlund E, Bengtsson-Stigmar E . Long-term follow-up of patients with uveitis associated with juvenile idiopathic arthritis: a cohort study. Ocul Immunol Inflamm. 2009; 17(2):104-8. DOI: 10.1080/09273940802650398. View

Sijssens K, Los L, Rothova A, Schellekens P, van de Does P, Stilma J . Long-term ocular complications in aphakic versus pseudophakic eyes of children with juvenile idiopathic arthritis-associated uveitis. Br J Ophthalmol. 2010; 94(9):1145-9. DOI: 10.1136/bjo.2009.167379. View

Saurenmann R, Levin A, Rose J, Parker S, Rabinovitch T, Tyrrell P . Tumour necrosis factor alpha inhibitors in the treatment of childhood uveitis. Rheumatology (Oxford). 2006; 45(8):982-9. DOI: 10.1093/rheumatology/kel030. View

Haas J, Truckenbrodt H, Paul C, Hoza J, Scholz S, Albert E . Subtypes of HLA-DRB1*03, *08, *11, *12, *13 and *14 in early onset pauciarticular juvenile chronic arthritis (EOPA) with and without iridocyclitis. Clin Exp Rheumatol. 1994; 12 Suppl 10:S7-14. View

Glass D, Litvin D, Wallace K, Chylack L, Garovoy M, Carpenter C . Early-onset pauciarticular juvenile rheumatoid arthritis associated with human leukocyte antigen-DRw5, iritis, and antinuclear antibody. J Clin Invest. 1980; 66(3):426-9. PMC: 371669. DOI: 10.1172/JCI109872. View

Thorne J, Woreta F, Kedhar S, Dunn J, Jabs D . Juvenile idiopathic arthritis-associated uveitis: incidence of ocular complications and visual acuity loss. Am J Ophthalmol. 2007; 143(5):840-846. DOI: 10.1016/j.ajo.2007.01.033. View

Sijssens K, Rothova A, van de Vijver D, Stilma J, de Boer J . Risk factors for the development of cataract requiring surgery in uveitis associated with juvenile idiopathic arthritis. Am J Ophthalmol. 2007; 144(4):574-9. DOI: 10.1016/j.ajo.2007.06.030. View

10.

Jabs D, Nussenblatt R, Rosenbaum J . Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005; 140(3):509-16. PMC: 8935739. DOI: 10.1016/j.ajo.2005.03.057. View

11.

Jensen A, Basti S, Greenwald M, Mets M . When may the posterior capsule be preserved in pediatric intraocular lens surgery?. Ophthalmology. 2002; 109(2):324-7; discussion 328. DOI: 10.1016/s0161-6420(01)00950-2. View

12.

Benezra D, Cohen E . Cataract surgery in children with chronic uveitis. Ophthalmology. 2000; 107(7):1255-60. DOI: 10.1016/s0161-6420(00)00160-3. View

13.

Acevedo S, Quinones K, Rao V, Cervantes-Castaneda R, Foster C . Cataract surgery in children with juvenile idiopathic arthritis associated uveitis. Int Ophthalmol Clin. 2008; 48(2):1-7. DOI: 10.1097/IIO.0b013e3181695b80. View

14.

Kotaniemi K, Kaipiainen-Seppanen O, Savolainen A, Karma A . A population-based study on uveitis in juvenile rheumatoid arthritis. Clin Exp Rheumatol. 1999; 17(1):119-22. View

15.

Ozdal P, Vianna R, Deschenes J . Visual outcome of juvenile rheumatoid arthritis-associated uveitis in adults. Ocul Immunol Inflamm. 2005; 13(1):33-8. DOI: 10.1080/09273940590909220. View

16.

Angeles-Han S, Flynn T, Lehman T . Abatacept for refractory juvenile idiopathic arthritis-associated uveitis- a case report. J Rheumatol. 2008; 35(9):1897-8. View

17.

Papaliodis G, Nguyen Q, Samson C, Foster C . Intraocular lens tolerance in surgery for cataracta complicata: assessment of four implant materials. Semin Ophthalmol. 2003; 17(3-4):120-3. DOI: 10.1076/soph.17.3.120.14788. View

18.

Kenawy N, Cleary G, Mewar D, Beare N, Chandna A, Pearce I . Abatacept: a potential therapy in refractory cases of juvenile idiopathic arthritis-associated uveitis. Graefes Arch Clin Exp Ophthalmol. 2010; 249(2):297-300. DOI: 10.1007/s00417-010-1523-6. View

19.

Zeggini E, Packham J, Donn R, Wordsworth P, Hall A, Thomson W . Association of HLA-DRB1*13 with susceptibility to uveitis in juvenile idiopathic arthritis in two independent data sets. Rheumatology (Oxford). 2006; 45(8):972-4. DOI: 10.1093/rheumatology/kel049. View

20.

Malagon C, van Kerckhove C, Giannini E, Taylor J, Lovell D, LEVINSON J . The iridocyclitis of early onset pauciarticular juvenile rheumatoid arthritis: outcome in immunogenetically characterized patients. J Rheumatol. 1992; 19(1):160-3. View