Long-term Follow-up of Patients with Uveitis Associated with Juvenile Idiopathic Arthritis: a Cohort Study

Overview

Journal Ocul Immunol Inflamm

Publisher Informa Healthcare

Specialty Ophthalmology

Date 2009 May 5

PMID 19412872

Citations 23

Authors

Angelika Skarin

Renate Elborgh

Eva Edlund

Elisabeth Bengtsson-Stigmar

Affiliations

Soon will be listed here.

Abstract

Purpose: To analyze the clinical and visual outcome of 55 consecutive patients with juvenile idiopathic arthritis (JIA)-associated uveitis examined 7 and 24 years after the onset of the eye disease.

Methods: A retrospective study.

Results: Fifty-five out of 350 patients with JIA developed uveitis (15.7%). Forty-six (84%) of these had oligoarthritis, 6 (11%) had polyarthritis, and 3(5%) had systemic disease. Cataract was present in 42% at 7 years and in 51% at 24 years. Uveitic glaucoma was present in 5% at 7 years and in 22% at 24 years. After 24 years, 27 patients (49%) still had active uveitis.

Conclusions: In half of these patients the uveitis was still active after 24 years of eye disease. In the group of patients with active disease, cataract and secondary glaucoma increased significantly between years 7 and 24 of disease.

Citing Articles

Reducing the risk of visual disability for children with juvenile idiopathic arthritis uveitis through disease surveillance: past and future challenges.

Solebo A, Foeldvari I Pediatr Rheumatol Online J. 2025; 23(1):4.

PMID: 39833902 PMC: 11744860. DOI: 10.1186/s12969-024-01037-4.

Uveitis associated with juvenile arthritis: a continued cohort study 40 years after uveitis onset.

Skarin A, Berthold E, Rauer O, Bengtsson-Stigmar E Pediatr Rheumatol Online J. 2022; 20(1):47.

PMID: 35804416 PMC: 9264563. DOI: 10.1186/s12969-022-00704-8.

Development of a Nationally Agreed Core Clinical Dataset for Childhood Onset Uveitis.

Solebo A, Kellett S, Rahi J, Pattani R, Edelsten C, Dick A Front Pediatr. 2022; 10:881398.

PMID: 35799695 PMC: 9253543. DOI: 10.3389/fped.2022.881398.

Persistence of Juvenile Idiopathic Arthritis-Associated Uveitis in Adulthood: A Retrospective Study.

Paroli M, Abbouda A, Albanese G, Accorinti M, Falcione A, Spadea L J Clin Med. 2022; 11(9).

PMID: 35566597 PMC: 9101652. DOI: 10.3390/jcm11092471.

Improved clinical outcomes in patients with juvenile idiopathic arthritis associated uveitis in the last decade.

Wennink R, Ayuso V, Pameijer E, Dekkers C, Bozkir I, de Boer J Acta Ophthalmol. 2022; 100(7):781-787.

PMID: 35076174 PMC: 9786763. DOI: 10.1111/aos.15097.