NELSON Lung Cancer Screening Study

Overview

Journal Cancer Imaging

Publisher Springer Nature

Specialties Oncology
Radiology

Date 2011 Dec 22

PMID 22185865

Citations 81

Authors

Ying Ru Zhao

Xueqian Xie

Harry J de Koning

Willem P Mali

Rozemarijn Vliegenthart

Matthijs Oudkerk

Affiliations

Soon will be listed here.

Abstract

The Dutch-Belgian Randomized Lung Cancer Screening Trial (Dutch acronym: NELSON study) was designed to investigate whether screening for lung cancer by low-dose multidetector computed tomography (CT) in high-risk subjects will lead to a decrease in 10-year lung cancer mortality of at least 25% compared with a control group without screening. Since the start of the NELSON study in 2003, 7557 participants underwent CT screening, with scan rounds in years 1, 2, 4 and 6. In the current review, the design of the NELSON study including participant selection and the lung nodule management protocol, as well as results on validation of CT screening and first results on lung cancer screening are described.

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