Astroviruses in Rabbits

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2011 Dec 17

PMID 22172457

Citations 16

Authors

Vito Martella

Paschalina Moschidou

Pierfrancesco Pinto

Cristiana Catella

Constantina Desario

Vittorio Larocca

Elena Circella

Krisztian Banyai

Antonio Lavazza

Chiara Magistrali

Nicola Decaro

Canio Buonavoglia

Affiliations

Soon will be listed here.

Abstract

By screening rabbits with enterocolitis or enteritis complex and asymptomatic rabbits, we identified a novel astrovirus. The virus was distantly related (19.3%-23.7% aa identity) in the capsid precursor to other mammalian astroviruses within the Mamastrovirus genus. By using real-time reverse transcription PCR, with specific primers and probes and targeting a conserved stretch in open reading frame 1b, we found rabbit astrovirus in 10 (43%) of 23 samples from animals with enteric disease and in 25 (18%) of 139 samples from asymptomatic animals in Italy during 2005-2008. The mean and median titers in the positive animals were 10(2)× and 10(3)× greater, respectively, in the symptomatic animals than in the asymptomatic animals. These findings support the idea that rabbit astroviruses should be included in the diagnostic algorithm of rabbit enteric disease and animal experiments to increase information obtained about their epidemiology and potential pathogenic role.

Citing Articles

First Detection of Benign Rabbit Caliciviruses in Chile.

Smertina E, Keller L, Huang N, Flores-Benner G, Correa-Cuadros J, Duclos M Viruses. 2024; 16(3).

PMID: 38543804 PMC: 10974056. DOI: 10.3390/v16030439.

The Genomic and Genetic Evolution Analysis of Rabbit Astrovirus.

Zhao Q, Tian Y, Liu L, Jiang Y, Sun H, Tan S Vet Sci. 2022; 9(11).

PMID: 36356080 PMC: 9697364. DOI: 10.3390/vetsci9110603.

Detection of Astrovirus in a Cow with Neurological Signs by Nanopore Technology, Italy.

Zaccaria G, Lorusso A, Hierweger M, Malatesta D, Defourny S, Ruggeri F Viruses. 2020; 12(5).

PMID: 32403368 PMC: 7290991. DOI: 10.3390/v12050530.

Gastrointestinal Disease in Exotic Small Mammals.

Huynh M, Pignon C J Exot Pet Med. 2020; 22(2):118-131.

PMID: 32288678 PMC: 7106034. DOI: 10.1053/j.jepm.2013.05.004.

Comparative Analysis of RNA Virome Composition in Rabbits and Associated Ectoparasites.

Mahar J, Shi M, Hall R, Strive T, Holmes E J Virol. 2020; 94(11).

PMID: 32188733 PMC: 7269439. DOI: 10.1128/JVI.02119-19.

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