The IntAct Molecular Interaction Database in 2012

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2011 Nov 29

PMID 22121220

Citations 506

Authors

Samuel Kerrien

Bruno Aranda

Lionel Breuza

Alan Bridge

Fiona Broackes-Carter

Carol Chen

Margaret Duesbury

Marine Dumousseau

Marc Feuermann

Ursula Hinz

Christine Jandrasits

Rafael C Jimenez

Jyoti Khadake

Usha Mahadevan

Patrick Masson

Ivo Pedruzzi

Eric Pfeiffenberger

Pablo Porras

Arathi Raghunath

Bernd Roechert

Sandra Orchard

Henning Hermjakob

Affiliations

Soon will be listed here.

Abstract

IntAct is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. Two levels of curation are now available within the database, with both IMEx-level annotation and less detailed MIMIx-compatible entries currently supported. As from September 2011, IntAct contains approximately 275,000 curated binary interaction evidences from over 5000 publications. The IntAct website has been improved to enhance the search process and in particular the graphical display of the results. New data download formats are also available, which will facilitate the inclusion of IntAct's data in the Semantic Web. IntAct is an active contributor to the IMEx consortium (http://www.imexconsortium.org). IntAct source code and data are freely available at http://www.ebi.ac.uk/intact.

Citing Articles

The protein interactome of Escherichia coli carbohydrate metabolism.

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Shrinkage estimation of gene interaction networks in single-cell RNA sequencing data.

Vo D, Thorne T BMC Bioinformatics. 2024; 25(1):339.

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Kumar P, Kumar V, Sharma S, Sharma R, Warghat A Naunyn Schmiedebergs Arch Pharmacol. 2024; .

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Inferring Interaction Networks from Transcriptomic Data: Methods and Applications.

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