Nucleoside-diphosphate-kinase: a Pleiotropic Effector in Microbial Colonization Under Interdisciplinary Characterization

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2011 Nov 15

PMID 22079150

Citations 24

Authors

Ralee Spooner

Ozlem Yilmaz

Affiliations

Soon will be listed here.

Abstract

Emerging evidence identifies multiple roles for nucleoside-diphosphate-kinase in host-microbe interaction. We provide the first synopsis of utilization of this molecule by various microorganisms during colonization of host tissues. Additionally, we propose novel mechanisms this effector may participate in, which could be crucial for microbial adaptation in chronic host infection.

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References

Sorice M, Circella A, Cristea I, Garofalo T, Di Renzo L, Alessandri C . Cardiolipin and its metabolites move from mitochondria to other cellular membranes during death receptor-mediated apoptosis. Cell Death Differ. 2004; 11(10):1133-45. DOI: 10.1038/sj.cdd.4401457. View

Dar H, Prasad D, Varshney G, Chakraborti P . Secretory nucleoside diphosphate kinases from both intra- and extracellular pathogenic bacteria are functionally indistinguishable. Microbiology (Reading). 2011; 157(Pt 11):3024-3035. DOI: 10.1099/mic.0.049221-0. View

Mileo A, Piombino E, Severino A, Tritarelli A, Paggi M, Lombardi D . Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein. J Bioenerg Biomembr. 2006; 38(3-4):215-25. DOI: 10.1007/s10863-006-9037-y. View

Yilmaz O, Verbeke P, Lamont R, Ojcius D . Intercellular spreading of Porphyromonas gingivalis infection in primary gingival epithelial cells. Infect Immun. 2005; 74(1):703-10. PMC: 1346639. DOI: 10.1128/IAI.74.1.703-710.2006. View

Melnikov A, Zaborina O, Dhiman N, Prabhakar B, Chakrabarty A, Hendrickson W . Clinical and environmental isolates of Burkholderia cepacia exhibit differential cytotoxicity towards macrophages and mast cells. Mol Microbiol. 2000; 36(6):1481-93. DOI: 10.1046/j.1365-2958.2000.01976.x. View

Souza T, Trindade D, Tonoli C, Santos C, Ward R, Arni R . Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding. Mol Biosyst. 2011; 7(7):2189-95. DOI: 10.1039/c0mb00307g. View

Kuehn M, Kesty N . Bacterial outer membrane vesicles and the host-pathogen interaction. Genes Dev. 2005; 19(22):2645-55. DOI: 10.1101/gad.1299905. View

Murakami M, Kaul R, Kumar P, Robertson E . Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus. Mol Cell Biochem. 2009; 329(1-2):131-9. PMC: 5958352. DOI: 10.1007/s11010-009-0123-4. View

Abdul-Sater A, Said-Sadier N, Ojcius D, Yilmaz O, Kelly K . Inflammasomes bridge signaling between pathogen identification and the immune response. Drugs Today (Barc). 2009; 45 Suppl B:105-12. PMC: 2829444. View

10.

Murakami M, Lan K, Subramanian C, Robertson E . Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration. J Virol. 2005; 79(3):1559-68. PMC: 544130. DOI: 10.1128/JVI.79.3.1559-1568.2005. View

11.

Colmenares M, Kar S, Goldsmith-Pestana K, McMahon-Pratt D . Mechanisms of pathogenesis: differences amongst Leishmania species. Trans R Soc Trop Med Hyg. 2002; 96 Suppl 1:S3-7. DOI: 10.1016/s0035-9203(02)90044-1. View

12.

Zhao Q, Yang M, Ting A, Logothetis D . PIP(2) regulates the ionic current of P2X receptors and P2X(7) receptor-mediated cell death. Channels (Austin). 2009; 1(1):46-55. View

13.

Huynh K, Plumb J, Downey G, Valvano M, Grinstein S . Inactivation of macrophage Rab7 by Burkholderia cenocepacia. J Innate Immun. 2010; 2(6):522-33. PMC: 2982851. DOI: 10.1159/000319864. View

14.

Nickel W . The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes. Eur J Biochem. 2003; 270(10):2109-19. DOI: 10.1046/j.1432-1033.2003.03577.x. View

15.

Kolli B, Kostal J, Zaborina O, Chakrabarty A, Chang K . Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages. Mol Biochem Parasitol. 2008; 158(2):163-75. PMC: 2277215. DOI: 10.1016/j.molbiopara.2007.12.010. View

16.

Qin Z, Dai L, Toole B, Robertson E, Parsons C . Regulation of Nm23-H1 and cell invasiveness by Kaposi's sarcoma-associated herpesvirus. J Virol. 2011; 85(7):3596-606. PMC: 3067884. DOI: 10.1128/JVI.01596-10. View

17.

Narita S . ABC transporters involved in the biogenesis of the outer membrane in gram-negative bacteria. Biosci Biotechnol Biochem. 2011; 75(6):1044-54. DOI: 10.1271/bbb.110115. View

18.

Yilmaz O, Yao L, Maeda K, Rose T, Lewis E, Duman M . ATP scavenging by the intracellular pathogen Porphyromonas gingivalis inhibits P2X7-mediated host-cell apoptosis. Cell Microbiol. 2007; 10(4):863-75. PMC: 2637656. DOI: 10.1111/j.1462-5822.2007.01089.x. View

19.

Lee M, Miller E . Molecular mechanisms of COPII vesicle formation. Semin Cell Dev Biol. 2007; 18(4):424-34. DOI: 10.1016/j.semcdb.2007.06.007. View

20.

Mehta A, Orchard S . Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified. Mol Cell Biochem. 2009; 329(1-2):3-15. PMC: 2721137. DOI: 10.1007/s11010-009-0114-5. View