The Initial Presentation of Systemic Lupus Erythematosis with Aplastic Anemia Successfully Treated with Rituximab

Overview

Journal Clin Rheumatol

Publisher Springer

Specialty Rheumatology

Date 2011 Oct 22

PMID 22015937

Citations 8

Authors

Gholam-Hossein Alishiri

Amin Saburi

Noushin Bayat

Ali-Reza Saadat

Ehsan Saburi

Affiliations

Soon will be listed here.

Abstract

Hematologic disorders are common in autoimmune diseases. First presentation of systemic lupus erythematosis with aplastic anemia is extremely rare. We report a patient with the diagnosis of secondary aplastic anemia associated with lupus. All routine medications were not effective. She received Rituximab and her response was satisfactory. Her hematologic parameters were within normal range until last follow-up, six months after therapy was initiated with Rituximab. Review of literature displayed 23 cases of acquired aplastic anemia secondary to systemic lupus erythematosis; however, this is the first time the new drug therapy was used for the treatment.

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Aplastic anemia as a feature of systemic lupus erythematosus: a case report and literature review.

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