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New Heterocyclic Derivatives of Benzimidazole with Germicidal Activity--VII--2-(5'-nitro-2'-furyl or 2'-thienyl) Benzimidazoles with Different Substituents in the 5-position

Overview
Journal Farmaco
Publisher Elsevier
Specialties Chemistry
Pharmacology
Date 1990 Mar 1
PMID 2200421
Citations 1
Authors
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Abstract

In continuation of our previous research, the synthesis of 13 2-(5'-nitro-2'-furyl or 2'-thienyl) benzimidazoles with different substituents in 5 position is described. The new compounds were tested in vitro against 5 (Gram+) and 4 (Gram-) strains and a mycete Candida Albicans. All the derivatives showed a certain degree of antibacterial and antimycotic activity, which in some cases was fairly good.

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