Containment of an Outbreak of KPC-3-producing Klebsiella Pneumoniae in Italy

Overview

Journal J Clin Microbiol

Specialty Microbiology

Date 2011 Sep 9

PMID 21900525

Citations 26

Authors

Antonella Agodi

Evangelia Voulgari

Martina Barchitta

Leda Politi

Vasiliki Koumaki

Nicholas Spanakis

Loredana Giaquinta

Giovanna Valenti

Maria Antonietta Romeo

Athanassios Tsakris

Affiliations

Soon will be listed here.

Abstract

From March 2009 to May 2009, 24 carbapenem-resistant Klebsiella pneumoniae isolates were recovered from 16 patients hospitalized in an Italian intensive care unit (ICU). All isolates contained KPC-3 carbapenemase and belonged to a single pulsed-field gel electrophoresis (PFGE) clone of multilocus sequence type 258 (designated as ST258). A multimodal infection control program was put into effect, and the spread of the KPC-3-producing K. pneumoniae clone was ultimately controlled without closing the ICU to new admissions. Reinforced infection control measures and strict monitoring of the staff adherence were necessary for the control of the outbreak.

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