Randomized, Controlled Trial of a 10-day Course of Amifloxacin Versus Trimethoprim-sulfamethoxazole in the Treatment of Acute, Uncomplicated Urinary Tract Infection. Amifloxacin Multi-Center Trial Group

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 1990 Apr 1

PMID 2188590

Citations 2

Authors

E J Boyko

A Iravani

M H Silverman

D J Schelling

R A Wright

Affiliations

Soon will be listed here.

Abstract

We conducted a randomized controlled trial of orally administered amifloxacin versus trimethoprimsulfamethoxazole (TMP-SMX) as treatments of acute uncomplicated urinary tract infection in women. Amifloxacin at a dosage of 200 mg twice a day appeared as safe and effective as TMP-SMX, but amifloxacin at 400 mg twice a day tended to cause adverse events more frequently than did TMP-SMX.

Citing Articles

Quinolones for uncomplicated acute cystitis in women.

Rafalsky V, Andreeva I, Rjabkova E Cochrane Database Syst Rev. 2006; (3):CD003597.

PMID: 16856014 PMC: 7003573. DOI: 10.1002/14651858.CD003597.pub2.

Comparative, double-blind, prospective, multicenter trial of temafloxacin versus trimethoprim-sulfamethoxazole in uncomplicated urinary tract infections in women.

Iravani A Antimicrob Agents Chemother. 1991; 35(9):1777-81.

PMID: 1952847 PMC: 245267. DOI: 10.1128/AAC.35.9.1777.

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