Cistrome: an Integrative Platform for Transcriptional Regulation Studies

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2011 Aug 24

PMID 21859476

Citations 453

Authors

Tao Liu

Jorge A Ortiz

Len Taing

Clifford A Meyer

Bernett Lee

Yong Zhang

Hyunjin Shin

Swee S Wong

Jian Ma

Ying Lei

Utz J Pape

Michael Poidinger

Yiwen Chen

Kevin Yeung

Myles Brown

Yaron Turpaz

X Shirley Liu

Affiliations

Soon will be listed here.

Abstract

The increasing volume of ChIP-chip and ChIP-seq data being generated creates a challenge for standard, integrative and reproducible bioinformatics data analysis platforms. We developed a web-based application called Cistrome, based on the Galaxy open source framework. In addition to the standard Galaxy functions, Cistrome has 29 ChIP-chip- and ChIP-seq-specific tools in three major categories, from preliminary peak calling and correlation analyses to downstream genome feature association, gene expression analyses, and motif discovery. Cistrome is available at http://cistrome.org/ap/.

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