DNA Replication: Mammalian Treslin-TopBP1 Interaction Mirrors Yeast Sld3-Dpb11

Overview

Journal Curr Biol

Publisher Cell Press

Specialty Biology

Date 2011 Aug 23

PMID 21855008

Citations 13

Authors

Adam C Mueller

Mignon A Keaton

Anindya Dutta

Affiliations

Soon will be listed here.

Abstract

There are many parallels between DNA replication in yeast and humans. Now, two recent studies extend this relationship by dissecting key conserved interactions necessary for initiation of the replisome.

Citing Articles

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The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition.

Zonderland G, Vanzo R, Gadi S, Martin-Doncel E, Coscia F, Mund A Mol Cell. 2022; 82(18):3350-3365.e7.

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Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1.

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Congenital Diseases of DNA Replication: Clinical Phenotypes and Molecular Mechanisms.

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