Differential Regulation of the Immune Response in the Spleen and Liver of Mice Infected with Leishmania Donovani

Overview

Journal J Trop Med

Publisher Wiley

Specialty Tropical Medicine

Date 2011 Aug 4

PMID 21811511

Citations 31

Authors

Rashmi Bankoti

Simona Stager

Affiliations

Soon will be listed here.

Abstract

Immunity to pathogens requires generation of effective innate and adaptive immune responses. Leishmania donovani evades these host defense mechanisms to survive and persist in the host. A better understanding and identification of mechanisms that L. donovani employs for its survival is critical for developing novel therapeutic interventions that specifically target the parasite. This paper will highlight some of the mechanisms that the parasite utilizes for its persistence and also discuss how the immune response is regulated.

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