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Ganglioneuroblastoma of the Posterior Mediastinum: a Case Report

Overview
Journal J Med Case Rep
Publisher Biomed Central
Specialty General Medicine
Date 2011 Jul 26
PMID 21781292
Citations 7
Authors
Saulat H Fatimi
Samira A Bawany
Awais Ashfaq
Affiliations
Soon will be listed here.
Abstract

Introduction: Ganglioneuroblastoma is a rare peripheral neuroblastic tumor that is derived from developing neuronal cells of the sympathetic nervous system, and is found mostly, but not exclusively, in babies and young children.

Case Presentation: To the best of our knowledge, there have been no previously reported cases of ganglioneuroblastoma of the mediastinum from Pakistan. We present a case of ganglioneuroblastoma in an eight-year-old Pakistani Sindhi boy incidentally found to have a large posterior mediastinal mass that on biopsy initially looked like ganglioneuroma. He underwent successful excision of the mediastinal mass and remained stable post-operatively. Final pathology findings showed a ganglioneuroblastoma. He has remained free of symptoms on long-term follow-up.

Conclusions: The rarity of this tumor along with its almost exclusive occurrence in the pediatric population necessitates a thorough investigation of patients presenting with a symptomatic mass.

Citing Articles

A needle in the haystack: An unusual case presentation of ganglioneuroblastoma at a tertiary care center in Coastal Karnataka.

Radhakrishnan S, Rao R, Lashkari H, Kini H, Kini J, Kudurugundi V Clin Case Rep. 2023; 11(11):e8149.

PMID: 38028045 PMC: 10665580. DOI: 10.1002/ccr3.8149.

Nonspecific Gastrointestinal Symptoms as the First Sign of Ganglioneuroblastoma Intermixed-Case Report and Literature Review.

Lipinski L, Lipinska J, Kowalczuk M, Kopec I, Wozniak M, Mitek-Palusinska J J Clin Med. 2023; 12(18).

PMID: 37763032 PMC: 10531539. DOI: 10.3390/jcm12186092.

Posterior mediastinal ganglioneuroblastoma in an adolescent: A case report and review.

Sekiguchi N, Noguchi T, Fukushima T, Kobayashi T, Ozawa T, Sato Y Thorac Cancer. 2019; 11(2):451-455.

PMID: 31837198 PMC: 6996985. DOI: 10.1111/1759-7714.13277.

Primary cervical ganglioneuroblastoma: A case report.

Lu D, Liu J, Chen Y, Chen F, Yang H Medicine (Baltimore). 2018; 97(12):e0090.

PMID: 29561407 PMC: 5895351. DOI: 10.1097/MD.0000000000010090.

Adult hippocampal ganglioneuroblastoma: Case report and literature review.

Yao P, Chen G, Shang-Guan H, Lin Q, Wang X, Zheng S Medicine (Baltimore). 2018; 96(51):e8894.

PMID: 29390424 PMC: 5758126. DOI: 10.1097/MD.0000000000008894.

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