Sister Mary Joseph Nodule-A Case Report with Review of Literature
Overview
Affiliations
Sister Mary Joseph nodule or Sister Mary Joseph Sign refers to a palpable nodule bulging into the umbilicus as a result of metastasis of a malignant cancer in the pelvis or abdomen. A rare case of Sister Mary Joseph nodule, manifesting as ascites, cachexia and bleeding per rectum, is presented without any primary tumor despite extensive search for the same.
Ben Ismail I, Mlika M, Manai G, Rebii S, Karma K, Zoghlami A Heliyon. 2025; 11(4):e42449.
PMID: 40028571 PMC: 11872107. DOI: 10.1016/j.heliyon.2025.e42449.
Sister Mary Joseph's Nodule as a Cutaneous Expression of Metastatic Pancreatic Adenocarcinoma.
Custer M, Lock S, Klemm K Cureus. 2024; 16(9):e69944.
PMID: 39445292 PMC: 11496047. DOI: 10.7759/cureus.69944.
Long-term survival of the Sister Mary Joseph nodule originating from breast cancer: A case report.
Kanayama K, Tanioka M, Hattori Y, Iida T, Okazaki M World J Clin Cases. 2023; 11(34):8205-8211.
PMID: 38130790 PMC: 10731175. DOI: 10.12998/wjcc.v11.i34.8205.
Sister Mary Joseph's Nodule From Renal Cell Carcinoma: A Case Report.
Hirata K, Narabayashi M, Murashima T, Segawa T, Ohtsu S Cureus. 2022; 14(10):e30344.
PMID: 36407130 PMC: 9665911. DOI: 10.7759/cureus.30344.
Radical treatment of Sister Mary-Joseph nodule: case report and literature review.
Majdoubi A, Bouhout T, Harhar M, Mirry A, Badr S, El Harroudi T Pan Afr Med J. 2021; 40:161.
PMID: 34970403 PMC: 8683450. DOI: 10.11604/pamj.2021.40.161.28407.