» Articles » PMID: 21764917

Characterization of Components of the Staphylococcus Aureus MRNA Degradosome Holoenzyme-like Complex

Overview
Journal J Bacteriol
Specialty Microbiology
Date 2011 Jul 19
PMID 21764917
Citations 66
Authors
Affiliations
Soon will be listed here.
Abstract

Bacterial two-hybrid analysis identified the Staphylococcus aureus RNA degradosome-like complex to include RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, and a DEAD box RNA helicase. Results also revealed that the recently recognized RNase RnpA interacts with the S. aureus degradosome and that this interaction is conserved in other Gram-positive organisms.

Citing Articles

Tracing the intraspecies expansion of glyoxalase genes and their expanding roles across the genus Oryza.

Bhowal B, Hasija Y, Singla-Pareek S Funct Integr Genomics. 2024; 24(6):220.

PMID: 39586889 DOI: 10.1007/s10142-024-01492-y.


Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus.

Le Scornet A, Jousselin A, Baumas K, Kostova G, Durand S, Poljak L PLoS Genet. 2024; 20(8):e1011349.

PMID: 39088561 PMC: 11321564. DOI: 10.1371/journal.pgen.1011349.


Heme utilization by the enterococci.

Brunson D, Lemos J FEMS Microbes. 2024; 5:xtae019.

PMID: 39070772 PMC: 11282960. DOI: 10.1093/femsmc/xtae019.


DEAD Box RNA Helicases: Biochemical Properties, Role in RNA Processing and Ribosome Biogenesis.

Hussain A Cell Biochem Biophys. 2024; 82(2):427-434.

PMID: 38430409 DOI: 10.1007/s12013-024-01240-w.


The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis in vitro.

Wicke D, Neumann P, Gossringer M, Chernev A, Davydov S, Poehlein A Nucleic Acids Res. 2023; 52(3):1404-1419.

PMID: 38050972 PMC: 10853771. DOI: 10.1093/nar/gkad1171.


References
1.
Carpousis A . The Escherichia coli RNA degradosome: structure, function and relationship in other ribonucleolytic multienzyme complexes. Biochem Soc Trans. 2002; 30(2):150-5. View

2.
Shi Z, Yang W, Lin-Chao S, Chak K, Yuan H . Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation. RNA. 2008; 14(11):2361-71. PMC: 2578853. DOI: 10.1261/rna.1244308. View

3.
Mathy N, Benard L, Pellegrini O, Daou R, Wen T, Condon C . 5'-to-3' exoribonuclease activity in bacteria: role of RNase J1 in rRNA maturation and 5' stability of mRNA. Cell. 2007; 129(4):681-92. DOI: 10.1016/j.cell.2007.02.051. View

4.
Kang S, Caparon M, Cho K . Virulence gene regulation by CvfA, a putative RNase: the CvfA-enolase complex in Streptococcus pyogenes links nutritional stress, growth-phase control, and virulence gene expression. Infect Immun. 2010; 78(6):2754-67. PMC: 2876558. DOI: 10.1128/IAI.01370-09. View

5.
Olson P, Kuechenmeister L, Anderson K, Daily S, Beenken K, Roux C . Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis. PLoS Pathog. 2011; 7(2):e1001287. PMC: 3037362. DOI: 10.1371/journal.ppat.1001287. View