The Cytomegalovirus Enhancer: a Pan-active Control Element in Transgenic Mice

Overview

Journal Mol Cell Biol

Specialty Cell Biology

Date 1990 Aug 1

PMID 2164640

Citations 75

Authors

E V SCHMIDT

G Christoph

R Zeller

P Leder

Affiliations

Soon will be listed here.

Abstract

In an effort to identify widely active positive regulatory elements, we have examined the action of the cytomegalovirus enhancer-promoter in transgenic mice. These elements activated expression in 24 of 28 tissues tested. The greatest expression was observed in the heart, kidney, brain, and testis. Maximum expression further localized to specific cells within the heart and kidney.

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