The Thrombotic Potential of Oral Pathogens

Overview

Journal J Oral Microbiol

Specialty Dentistry

Date 2011 Apr 28

PMID 21523210

Citations 2

Authors

Steven W Kerrigan

Dermot Cox

Affiliations

Soon will be listed here.

Abstract

In recent times the concept of infectious agents playing a role in cardiovascular disease has attracted much attention. Chronic oral disease such as periodontitis, provides a plausible route for entry of bacteria to the circulation. Upon entry to the circulation, the oral bacteria interact with platelets. It has been proposed that their ability to induce platelet aggregation and support platelet adhesion is a critical step in the pathogenesis of the infection process. Many published studies have demonstrated multiple mechanisms through which oral bacteria are able to bind to and activate platelets. This paper will review the various mechanisms oral bacteria use to interact with platelets.

Citing Articles

Association between Oral Pathology, Carotid Stenosis, and Oral Bacterial DNA in Cerebral Thrombi of Patients with Stroke.

Patrakka O, Mehtonen H, Tuomisto S, Pienimaki J, Ollikainen J, Huhtala H Stroke Res Treat. 2021; 2021:5402764.

PMID: 34531969 PMC: 8440111. DOI: 10.1155/2021/5402764.

Oral Bacterial Signatures in Cerebral Thrombi of Patients With Acute Ischemic Stroke Treated With Thrombectomy.

Patrakka O, Pienimaki J, Tuomisto S, Ollikainen J, Lehtimaki T, Karhunen P J Am Heart Assoc. 2019; 8(11):e012330.

PMID: 31117858 PMC: 6585368. DOI: 10.1161/JAHA.119.012330.

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