Kidney Transplantation in Childhood: Mental Health and Quality of Life of Children and Caregivers

Overview

Journal Pediatr Nephrol

Specialties Nephrology
Pediatrics

Date 2011 Apr 27

PMID 21520007

Citations 15

Authors

Trond H Diseth

Trine Tangeraas

Trude Reinfjell

Anna Bjerre

Affiliations

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Abstract

Our objective was to assess the mental health and health-related quality of life (HRQOL) in children and their parents after renal transplantation (TX) compared to healthy controls and children with acute lymphoblastic leukemia (ALL) and to identify possible health status variables associated with impaired mental health and HRQOL. Thirty-eight TX children with a median age of 13 (range 3-19) years were investigated. Mental health was assessed by the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales and the Strength and Difficulties Questionnaire (SDQ-20). Each mother's own mental health and QOL were assessed by the General Health Questionnaire (GHQ-30) and the Quality of Life Scale (QOLS). Forty children with ALL [median age 11 (8.5-15.4) years] and 42 healthy children [median age 11 (8.9- 15) years] served as controls. Treadmill exercise results from 22 of the 38 patients were included in the analysis. TX children showed significantly higher levels of mental health problems and lower HRQOL at 2 to 16 years after transplantation compared to both control groups. Body mass index and maximal oxygen uptake (n = 22/38) were significant predictors of child mental health (SDQ) and child QOL (PedsQL), respectively. Based on these results, we suggest that rehabilitation after TX should include a focus on physical activity and QOL to reduce interconnected physical and psychological morbidity in kidney TX children.

Citing Articles

Is Non-Adherence Associated with Adverse Outcomes in Kidney Transplant Recipients? The Role of Non-Adherence as a Risk and Predictor Factor for Graft Loss and Death.

Torres-Gutierrez M, Lozano-Suarez N, Burgos-Camacho V, Caamano-Jaraba J, Gomez-Montero J, Garcia-Lopez A Patient Prefer Adherence. 2023; 17:2915-2925.

PMID: 38027086 PMC: 10648956. DOI: 10.2147/PPA.S436833.

Holistic care and symptom management for pediatric kidney transplant recipients.

House T, Marks S, Freeman M Pediatr Nephrol. 2023; 39(6):1759-1769.

PMID: 37851087 DOI: 10.1007/s00467-023-06175-7.

Quality of life of transplanted children and their parents: a cross-sectional study.

Duvant P, Fillat M, Garaix F, Roquelaure B, Ovaert C, Fouilloux V Orphanet J Rare Dis. 2021; 16(1):364.

PMID: 34404428 PMC: 8369793. DOI: 10.1186/s13023-021-01987-y.

Safeguarding children and young people requiring kidney replacement therapy: challenges and potential opportunities.

Jacob H, Marlais M Pediatr Nephrol. 2021; 37(5):1007-1015.

PMID: 34247294 DOI: 10.1007/s00467-021-05133-5.

Association of nutritional status and health-related quality of life in children with chronic kidney disease.

Harmer M, Wootton S, Gilbert R, Anderson C Qual Life Res. 2019; 28(6):1565-1573.

PMID: 30637552 PMC: 6522445. DOI: 10.1007/s11136-019-02104-0.

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