Treatment of Isolated Gastric Crohn's Disease with Inhaled Corticosteroids

Overview

Journal Case Rep Gastroenterol

Publisher Karger

Specialty Gastroenterology

Date 2011 Apr 15

PMID 21490870

Citations 7

Authors

Samar H Ibrahim

Thomas C Smyrk

William A Faubion

Affiliations

Soon will be listed here.

Abstract

Isolated gastric Crohn's disease is unusual and a rare cause of pyloric outlet obstruction. If medical therapy is ineffective, patients may require surgery to relieve gastric outlet obstruction. Herein we describe a patient with isolated gastric Crohn's disease with pyloric outlet obstruction who was steroid-dependent and had a relapse despite receiving biologic and immunomodulatory therapy, but ultimately responded to topical treatment with inhaled corticosteroids.

Citing Articles

A Classification for Gastric Outlet Obstruction in Childhood: Extending Beyond Infantile Hypertrophic Pyloric Stenosis.

Gurkan O, Ozturk H, Kaya C, Gurcan Kaya N, Eksi Bozbulut N, Can A Turk J Gastroenterol. 2024; 35(3):255-261.

PMID: 39128098 PMC: 11059985. DOI: 10.5152/tjg.2024.23202.

Drug Repurposing in Crohn's Disease Using Danish Real-World Data.

Shakibfar S, Allin K, Jess T, Barbieri M, Battini V, Simoncic E Pragmat Obs Res. 2024; 15:17-29.

PMID: 38404739 PMC: 10894518. DOI: 10.2147/POR.S444569.

Crohn's disease: An enigmatic variant with gastritis and ileal obstruction.

Amo-Tachie S, Ocansey F, Yeboah A Clin Case Rep. 2024; 12(1):e8371.

PMID: 38161629 PMC: 10753134. DOI: 10.1002/ccr3.8371.

Pediatric Crohn's disease with severe morbidity manifested by gastric outlet obstruction: two cases report and review of the literature.

Kim E, Park J, Choe Y, Kim M Intest Res. 2020; 19(4):472-477.

PMID: 33108856 PMC: 8566835. DOI: 10.5217/ir.2020.00072.

Pyloric stenosis as a manifestation of isolated gastric Crohn's disease responding to intralesional steroid injection and balloon dilation: a case report.

Balendran K, Udumalagala S, Nawaraththne N J Med Case Rep. 2019; 13(1):331.

PMID: 31718712 PMC: 6852991. DOI: 10.1186/s13256-019-2272-8.

References

Sandborn W . Preliminary report on the use of oral tacrolimus (FK506) in the treatment of complicated proximal small bowel and fistulizing Crohn's disease. Am J Gastroenterol. 1997; 92(5):876-9. View

Matsui T, Hatakeyama S, Ikeda K, Yao T, Takenaka K, Sakurai T . Long-term outcome of endoscopic balloon dilation in obstructive gastroduodenal Crohn's disease. Endoscopy. 1997; 29(7):640-5. DOI: 10.1055/s-2007-1004271. View

Grove A, Allam C, McFarlane L, McPhate G, Jackson C, Lipworth B . A comparison of the systemic bioactivity of inhaled budesonide and fluticasone propionate in normal subjects. Br J Clin Pharmacol. 1994; 38(6):527-32. PMC: 1364916. DOI: 10.1111/j.1365-2125.1994.tb04394.x. View

Kamada A, Szefler S, Martin R, Boushey H, Chinchilli V, Drazen J . Issues in the use of inhaled glucocorticoids. The Asthma Clinical Research Network. Am J Respir Crit Care Med. 1996; 153(6 Pt 1):1739-48. DOI: 10.1164/ajrccm.153.6.8665030. View

Feagan B, Fedorak R, Irvine E, Wild G, Sutherland L, Steinhart A . A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators. N Engl J Med. 2000; 342(22):1627-32. DOI: 10.1056/NEJM200006013422202. View

Futami K, Arima S . Role of strictureplasty in surgical treatment of Crohn's disease. J Gastroenterol. 2005; 40 Suppl 16:35-9. DOI: 10.1007/BF02990577. View

Tremaine W . Gastroduodenal Crohn's disease: medical management. Inflamm Bowel Dis. 2003; 9(2):127-8; discussion 131. DOI: 10.1097/00054725-200303000-00008. View

Faubion Jr W, Perrault J, Burgart L, Zein N, Clawson M, Freese D . Treatment of eosinophilic esophagitis with inhaled corticosteroids. J Pediatr Gastroenterol Nutr. 1998; 27(1):90-3. DOI: 10.1097/00005176-199807000-00016. View

Ross T, Fazio V, Farmer R . Long-term results of surgical treatment for Crohn's disease of the duodenum. Ann Surg. 1983; 197(4):399-406. PMC: 1352751. DOI: 10.1097/00000658-198304000-00004. View

10.

Priebe W, Simon J . Crohn's disease of the stomach with outlet obstruction: a case report and review of therapy. J Clin Gastroenterol. 1983; 5(5):441-5. DOI: 10.1097/00004836-198310000-00012. View

11.

Knapp A, Mirsky F, Dillon E, Korelitz B . Successful infliximab therapy for a duodenal stricture caused by Crohn's disease. Inflamm Bowel Dis. 2005; 11(12):1123-5. DOI: 10.1097/01.mib.0000191612.43584.94. View

12.

Murray J, Schoetz Jr D, Nugent F, Coller J, VEIDENHEIMER M . Surgical management of Crohn's disease involving the duodenum. Am J Surg. 1984; 147(1):58-65. DOI: 10.1016/0002-9610(84)90035-7. View

13.

Auvin S, Molinie F, Gower-Rousseau C, Brazier F, Merle V, Grandbastien B . Incidence, clinical presentation and location at diagnosis of pediatric inflammatory bowel disease: a prospective population-based study in northern France (1988-1999). J Pediatr Gastroenterol Nutr. 2005; 41(1):49-55. DOI: 10.1097/01.mpg.0000162479.74277.86. View

14.

Murthy U . Repeated hydrostatic balloon dilation in obstructive gastroduodenal Crohn's disease. Gastrointest Endosc. 1991; 37(4):484-5. DOI: 10.1016/s0016-5107(91)70789-x. View

15.

Fielding J, TOYE D, Beton D, COOKE W . Crohn's disease of the stomach and duodenum. Gut. 1970; 11(12):1001-6. PMC: 1553160. DOI: 10.1136/gut.11.12.1001. View