Role of Natural Product Diversity in Chemical Biology

Overview

Journal Curr Opin Chem Biol

Publisher Elsevier

Specialty Biochemistry

Date 2011 Apr 15

PMID 21489856

Citations 51

Authors

Jiyong Hong

Affiliations

Soon will be listed here.

Abstract

Through the natural selection process, natural products possess a unique and vast chemical diversity and have been evolved for optimal interactions with biological macromolecules. Owing to their diversity, target affinity, and specificity, natural products have demonstrated enormous potential as modulators of biomolecular function, been an essential source for drug discovery, and provided design principles for combinatorial library development.

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