Overview of the CCP4 Suite and Current Developments

Overview

Journal Acta Crystallogr D Biol Crystallogr

Specialty Chemistry

Date 2011 Apr 5

PMID 21460441

Citations 5918

Authors

Martyn D Winn

Charles C Ballard

Kevin D Cowtan

Eleanor J Dodson

Paul Emsley

Phil R Evans

Ronan M Keegan

Eugene B Krissinel

Andrew G W Leslie

Airlie McCoy

Stuart J McNicholas

Garib N Murshudov

Navraj S Pannu

Elizabeth A Potterton

Harold R Powell

Randy J Read

Alexei Vagin

Keith S Wilson

Affiliations

Soon will be listed here.

Abstract

The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of programs and associated data and software libraries which can be used for macromolecular structure determination by X-ray crystallography. The suite is designed to be flexible, allowing users a number of methods of achieving their aims. The programs are from a wide variety of sources but are connected by a common infrastructure provided by standard file formats, data objects and graphical interfaces. Structure solution by macromolecular crystallography is becoming increasingly automated and the CCP4 suite includes several automation pipelines. After giving a brief description of the evolution of CCP4 over the last 30 years, an overview of the current suite is given. While detailed descriptions are given in the accompanying articles, here it is shown how the individual programs contribute to a complete software package.

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