Heart Failure: Advances Through Genomics

Overview

Journal Nat Rev Genet

Specialty Genetics

Date 2011 Mar 23

PMID 21423240

Citations 36

Authors

Esther E Creemers

Arthur A Wilde

Yigal M Pinto

Affiliations

Soon will be listed here.

Abstract

Heart failure is an increasingly prevalent and highly lethal disease that is most often caused by underlying pathologies, such as myocardial infarction or hypertension, but it can also be the result of a single gene mutation. Comprehensive genetic and genomic approaches are starting to disentangle the diverse molecular underpinnings of both forms of the disease and promise to yield much-needed novel diagnostic and therapeutic options for specific subtypes of heart failure.

Citing Articles

Impact of rs1805127 and rs55742440 Variants on Atrial Remodeling in Hypertrophic Cardiomyopathy Patients with Atrial Fibrillation: A Romanian Cohort Study.

Popa-Fotea N, Oprescu N, Scafa-Udriste A, Micheu M Int J Mol Sci. 2023; 24(24).

PMID: 38139087 PMC: 10743528. DOI: 10.3390/ijms242417244.

Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure.

Gu M, Zhao Y, Wang H, Cheng W, Liu J, Ouyang K Int J Mol Sci. 2023; 24(2).

PMID: 36674797 PMC: 9867119. DOI: 10.3390/ijms24021283.

Deciphering the Basis of Molecular Biology of Selected Cardiovascular Diseases: A View on Network Medicine.

AlHajri N, Rustom M, Adegbile A, Ahmed W, Kilidar S, Afify N Int J Mol Sci. 2022; 23(19).

PMID: 36232723 PMC: 9569471. DOI: 10.3390/ijms231911421.

Association between ZFHX3 and PRRX1 Polymorphisms and Atrial Fibrillation Susceptibility from Meta-Analysis.

Wu L, Chu M, Zhuang W Int J Hypertens. 2021; 2021:9423576.

PMID: 34950514 PMC: 8692054. DOI: 10.1155/2021/9423576.

Complex Conformational Dynamics of the Heart Failure-Associated Pre-miRNA-377 Hairpin Revealed by Single-Molecule Optical Tweezers.

Wypijewska Del Nogal A, Sundar Rajan V, Westerlund F, Wilhelmsson L Int J Mol Sci. 2021; 22(16).

PMID: 34445712 PMC: 8396532. DOI: 10.3390/ijms22169008.

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