Vitamin D and Gastrointestinal Diseases: Inflammatory Bowel Disease and Colorectal Cancer

Overview

Journal Therap Adv Gastroenterol

Publisher Sage Publications

Specialty Gastroenterology

Date 2011 Feb 15

PMID 21317994

Citations 25

Authors

Maitreyi Raman

Andrew N Milestone

Julian R F Walters

Ailsa L Hart

Subrata Ghosh

Affiliations

Soon will be listed here.

Abstract

Over the past 5 years, there has been a rapid resurgence of interest in vitamin D outside of its traditional role in metabolic bone disease. Some nontraditional roles ascribed to vitamin D include anti-inflammatory and immune-modulating effects. These effects have led to possible implications in the pathophysiology of immune-mediated diseases including multiple sclerosis and inflammatory bowel disease (IBD). In addition, vitamin D insufficiency has been linked to higher rates of cancers including colon, prostate and breast cancers. Given these diverse associations of vitamin D and disease states, this review describes recent advances with regard to vitamin D and gastrointestinal diseases, in particular IBD and colorectal cancer.

Citing Articles

The Anti-Inflammatory Roles of Vitamin D for Improving Human Health.

Fenercioglu A Curr Issues Mol Biol. 2024; 46(12):13514-13525.

PMID: 39727935 PMC: 11674702. DOI: 10.3390/cimb46120807.

The role of vitamin D in treated and refractory ulcerative colitis patients: a case-control study.

Ahmadi A, Shokoohizadeh L, Sheikhesmaili F, Nikkhoo B, Mohammadi A, Khan Mirzaei M BMC Gastroenterol. 2024; 24(1):454.

PMID: 39695960 PMC: 11653863. DOI: 10.1186/s12876-024-03558-4.

Cause or effect? Undetectable vitamin D in a patient with Crohn's disease.

Esswein J, Vickers M, Kleinman M, Whitworth J, Corkins M, Riley Pace S JPGN Rep. 2024; 5(2):194-196.

PMID: 38756124 PMC: 11093929. DOI: 10.1002/jpr3.12045.

Infections and Autoimmunity-The Immune System and Vitamin D: A Systematic Review.

Wimalawansa S Nutrients. 2023; 15(17).

PMID: 37686873 PMC: 10490553. DOI: 10.3390/nu15173842.

Neuroimmunological Effect of Vitamin D on Neuropsychiatric Long COVID Syndrome: A Review.

Chen T, Chang C, Yang C, Tsai I, Wei C, Yang H Nutrients. 2023; 15(17).

PMID: 37686834 PMC: 10490318. DOI: 10.3390/nu15173802.

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