A Prospective, Randomized, Double-blind Comparison of 2% Mepivacaine with 1 : 20,000 Levonordefrin Versus 2% Lidocaine with 1 : 100,000 Epinephrine for Maxillary Infiltrations

Overview

Journal Anesth Prog

Specialties Anesthesiology
Dentistry

Date 2010 Dec 23

PMID 21174567

Citations 8

Authors

Ingrid Lawaty

Melissa Drum

Al Reader

John Nusstein

Affiliations

Soon will be listed here.

Abstract

The purpose of this prospective, randomized, double-blind crossover study was to compare the anesthetic efficacy of 2% mepivacaine with 1 : 20,000 levonordefrin versus 2% lidocaine with 1 : 100,000 epinephrine in maxillary central incisors and first molars. Sixty subjects randomly received, in a double-blind manner, maxillary central incisor and first molar infiltrations of 1.8 mL of 2% mepivacaine with 1 : 20,000 levonordefrin and 1.8 mL of 2% lidocaine with 1 : 100,000 epinephrine at 2 separate appointments spaced at least 1 week apart. The teeth were electric pulp tested in 2-minute cycles for a total of 60 minutes. Anesthetic success (obtaining 2 consecutive 80 readings with the electric pulp tester within 10 minutes) was not significantly different between 2% mepivacaine with 1 : 20,000 levonordefrin and 2% lidocaine with 1 : 100,000 epinephrine for the central incisor and first molar. However, neither anesthetic agent provided an hour of pulpal anesthesia.

Citing Articles

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Anesthetic efficacy in vital asymptomatic teeth using different local anesthetics: a systematic review with network meta-analysis.

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