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Vitamin E Status in Sudanese Children with Protein-energy Malnutrition

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Date 1990 Mar 1
PMID 2110395
Citations 2
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Abstract

Total tocopherols and alpha-tocopherols were estimated in the plasma of children with severe malnutrition (14 marasmus; 11 marasmic kwashiorkor; five kwashiorkor) and related to the total plasma lipids and different plasma lipid classes. If the mere plasma concentrations were taken as an index of the vitamin E status, five children with marasmus, five children with marasmic kwashiorkor, and two children with kwashiorkor would have been regarded as deficient (less than 500 micrograms/dl). However, if total tocopherols and alpha-tocopherols were related to the total plasma lipids, all malnourished children--except one--showed values within the limits found in healthy American children. The study shows that low tocopherol/lipid ratios are not a constant feature in severely malnourished children.

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References
1.
Cheek C, Wease D . A summation technic for serum total lipids. Comparison of methods. Clin Chem. 1969; 15(2):102-7. View

2.
BIERI J, Tolliver T, Catignani G . Simultaneous determination of alpha-tocopherol and retinol in plasma or red cells by high pressure liquid chromatography. Am J Clin Nutr. 1979; 32(10):2143-9. DOI: 10.1093/ajcn/32.10.2143. View

3.
Horwitt M, HARVEY C, Dahm Jr C, Searcy M . Relationship between tocopherol and serum lipid levels for determination of nutritional adequacy. Ann N Y Acad Sci. 1972; 203:223-36. DOI: 10.1111/j.1749-6632.1972.tb27878.x. View

4.
Cornblath M, GORDON H, NITOWSKY H . Studies of tocopherol deficiency in infants and children. II. Plasma tocopherol and erythrocyte hemolysis in hydrogen peroxide. AMA J Dis Child. 1956; 92(2):164-74. DOI: 10.1001/archpedi.1956.02060030158010. View

5.
ZILVERSMIT D, Davis A . Microdetermination of plasma phospholipids by trichloroacetic acid precipitation. J Lab Clin Med. 1950; 35(1):155-60. View