Hippo Signaling at a Glance

Overview

Journal J Cell Sci

Specialty Cell Biology

Date 2010 Nov 19

PMID 21084559

Citations 63

Authors

Bin Zhao

Li Li

Kun-Liang Guan

Affiliations

Soon will be listed here.

Citing Articles

Differential age-related transcriptomic analysis of ovarian granulosa cells in Kazakh horses.

Ren W, Wang J, Zeng Y, Wang T, Meng J, Yao X Front Endocrinol (Lausanne). 2024; 15:1346260.

PMID: 38352714 PMC: 10863452. DOI: 10.3389/fendo.2024.1346260.

The role of matrix stiffness in breast cancer progression: a review.

Xu R, Yin P, Wei J, Ding Q Front Oncol. 2023; 13:1284926.

PMID: 37916166 PMC: 10616305. DOI: 10.3389/fonc.2023.1284926.

Molecular Mechanisms of Anti-Estrogen Therapy Resistance and Novel Targeted Therapies.

Ozyurt R, Ozpolat B Cancers (Basel). 2022; 14(21).

PMID: 36358625 PMC: 9655708. DOI: 10.3390/cancers14215206.

Tubular cell polyploidy protects from lethal acute kidney injury but promotes consequent chronic kidney disease.

De Chiara L, Conte C, Semeraro R, Diaz-Bulnes P, Angelotti M, Mazzinghi B Nat Commun. 2022; 13(1):5805.

PMID: 36195583 PMC: 9532438. DOI: 10.1038/s41467-022-33110-5.

Characteristics of the cancer stem cell niche and therapeutic strategies.

Ju F, Atyah M, Horstmann N, Gul S, Vago R, Bruns C Stem Cell Res Ther. 2022; 13(1):233.

PMID: 35659296 PMC: 9166529. DOI: 10.1186/s13287-022-02904-1.

References

Zhang H, Liu C, Zha Z, Zhao B, Yao J, Zhao S . TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem. 2009; 284(20):13355-13362. PMC: 2679435. DOI: 10.1074/jbc.M900843200. View

Chan S, Lim C, Guo K, Peng Ng C, Lee I, Hunziker W . A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells. Cancer Res. 2008; 68(8):2592-8. DOI: 10.1158/0008-5472.CAN-07-2696. View

Hergovich A, Schmitz D, Hemmings B . The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochem Biophys Res Commun. 2006; 345(1):50-8. DOI: 10.1016/j.bbrc.2006.03.244. View

Camargo F, Gokhale S, Johnnidis J, Fu D, Bell G, Jaenisch R . YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol. 2007; 17(23):2054-60. DOI: 10.1016/j.cub.2007.10.039. View

Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T . Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol. 2008; 294(3):F542-53. DOI: 10.1152/ajprenal.00201.2007. View

Callus B, Verhagen A, Vaux D . Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. FEBS J. 2006; 273(18):4264-76. DOI: 10.1111/j.1742-4658.2006.05427.x. View

Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C . The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol. 2005; 8(1):27-36. DOI: 10.1038/ncb1339. View

Udan R, Kango-Singh M, Nolo R, Tao C, Halder G . Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nat Cell Biol. 2003; 5(10):914-20. DOI: 10.1038/ncb1050. View

Badouel C, Gardano L, Amin N, Garg A, Rosenfeld R, Le Bihan T . The FERM-domain protein Expanded regulates Hippo pathway activity via direct interactions with the transcriptional activator Yorkie. Dev Cell. 2009; 16(3):411-20. DOI: 10.1016/j.devcel.2009.01.010. View

10.

Pantalacci S, Tapon N, Leopold P . The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nat Cell Biol. 2003; 5(10):921-7. DOI: 10.1038/ncb1051. View

11.

Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y . The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A. 2010; 107(23):10532-7. PMC: 2890787. DOI: 10.1073/pnas.1004279107. View

12.

Willecke M, Hamaratoglu F, Kango-Singh M, Udan R, Chen C, Tao C . The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Curr Biol. 2006; 16(21):2090-100. DOI: 10.1016/j.cub.2006.09.005. View

13.

Tian W, Yu J, Tomchick D, Pan D, Luo X . Structural and functional analysis of the YAP-binding domain of human TEAD2. Proc Natl Acad Sci U S A. 2010; 107(16):7293-8. PMC: 2867681. DOI: 10.1073/pnas.1000293107. View

14.

Chen L, Chan S, Zhang X, Walsh M, Lim C, Hong W . Structural basis of YAP recognition by TEAD4 in the hippo pathway. Genes Dev. 2010; 24(3):290-300. PMC: 2811830. DOI: 10.1101/gad.1865310. View

15.

Li Z, Zhao B, Wang P, Chen F, Dong Z, Yang H . Structural insights into the YAP and TEAD complex. Genes Dev. 2010; 24(3):235-40. PMC: 2811825. DOI: 10.1101/gad.1865810. View

16.

Justice R, Zilian O, Woods D, Noll M, Bryant P . The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev. 1995; 9(5):534-46. DOI: 10.1101/gad.9.5.534. View

17.

Silva E, Tsatskis Y, Gardano L, Tapon N, McNeill H . The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway. Curr Biol. 2006; 16(21):2081-9. DOI: 10.1016/j.cub.2006.09.004. View

18.

Wei X, Shimizu T, Lai Z . Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J. 2007; 26(7):1772-81. PMC: 1847660. DOI: 10.1038/sj.emboj.7601630. View

19.

Thompson B, Cohen S . The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell. 2006; 126(4):767-74. DOI: 10.1016/j.cell.2006.07.013. View

20.

Xu T, Wang W, Zhang S, Stewart R, Yu W . Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development. 1995; 121(4):1053-63. DOI: 10.1242/dev.121.4.1053. View