The Art of Engineering Viral Nanoparticles

Overview

Journal Mol Pharm

Publisher American Chemical Society

Specialty Pharmacology

Date 2010 Nov 5

PMID 21047140

Citations 77

Authors

Jonathan K Pokorski

Nicole F Steinmetz

Affiliations

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Abstract

Viral nanotechnology is an emerging and highly interdisciplinary field in which viral nanoparticles (VNPs) are applied in diverse areas such as electronics, energy and next-generation medical devices. VNPs have been developed as candidates for novel materials, and are often described as "programmable" because they can be modified and functionalized using a number of techniques. In this review, we discuss the concepts and methods that allow VNPs to be engineered, including (i) bioconjugation chemistries, (ii) encapsulation techniques, (iii) mineralization strategies, and (iv) film and hydrogel development. With all these techniques in hand, the potential applications of VNPs are limited only by the imagination.

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