The Protein Ontology: a Structured Representation of Protein Forms and Complexes

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2010 Oct 12

PMID 20935045

Citations 61

Authors

Darren A Natale

Cecilia N Arighi

Winona C Barker

Judith A Blake

Carol J Bult

Michael Caudy

Harold J Drabkin

Peter DEustachio

Alexei V Evsikov

Hongzhan Huang

Jules Nchoutmboube

Natalia V Roberts

Barry Smith

Jian Zhang

Cathy H Wu

Affiliations

Soon will be listed here.

Abstract

The Protein Ontology (PRO) provides a formal, logically-based classification of specific protein classes including structured representations of protein isoforms, variants and modified forms. Initially focused on proteins found in human, mouse and Escherichia coli, PRO now includes representations of protein complexes. The PRO Consortium works in concert with the developers of other biomedical ontologies and protein knowledge bases to provide the ability to formally organize and integrate representations of precise protein forms so as to enhance accessibility to results of protein research. PRO (http://pir.georgetown.edu/pro) is part of the Open Biomedical Ontology Foundry.

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