Alexei V Evsikov
Overview
Explore the profile of Alexei V Evsikov including associated specialties, affiliations and a list of published articles.
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20
Citations
899
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Recent Articles
1.
Egbert J, Fahey P, Reimer J, Owen C, Evsikov A, Nikolaev V, et al.
Biol Reprod
. 2019 May;
101(2):433-444.
PMID: 31087036
In mammalian ovarian follicles, follicle stimulating hormone (FSH) and luteinizing hormone (LH) signal primarily through the G-protein Gs to elevate cAMP, but both of these hormones can also elevate Ca2+...
2.
Marin de Evsikova C, Raplee I, Lockhart J, Jaimes G, Evsikov A
J Pers Med
. 2019 Apr;
9(2).
PMID: 31032818
As one of the most widespread metabolic diseases, atherosclerosis affects nearly everyone as they age; arteries gradually narrow from plaque accumulation over time reducing oxygenated blood flow to central and...
3.
Raplee I, Evsikov A, Marin de Evsikova C
J Pers Med
. 2019 Apr;
9(2).
PMID: 30987214
The rapid expansion of transcriptomics and affordability of next-generation sequencing (NGS) technologies generate rocketing amounts of gene expression data across biology and medicine, including cancer research. Concomitantly, many bioinformatics tools...
4.
Evsikov A, Marin de Evsikova C
Yale J Biol Med
. 2016 Dec;
89(4):487-497.
PMID: 28018140
Epigenetics is the study of phenotypic variation arising from developmental and environmental factors regulating gene transcription at molecular, cellular, and physiological levels. A naturally occurring biological process driven by epigenetics...
5.
Bais P, Beebe K, Morelli K, Currie M, Norberg S, Evsikov A, et al.
Biol Open
. 2016 Jun;
5(7):908-20.
PMID: 27288508
Charcot-Marie-Tooth disease encompasses a genetically heterogeneous class of heritable polyneuropathies that result in axonal degeneration in the peripheral nervous system. Charcot-Marie-Tooth type 2D neuropathy (CMT2D) is caused by dominant mutations...
6.
Han M, Evsikov A, Zhang L, Lastra-Vicente R, Linask K
Reprod Toxicol
. 2016 Mar;
61:82-96.
PMID: 26993217
Embryonic exposures can increase the risk of congenital cardiac birth defects and adult disease. The present study identifies the predominant pathways modulated by an acute embryonic mouse exposure during gastrulation...
7.
Bernhardt M, Lowther K, Padilla-Banks E, McDonough C, Lee K, Evsikov A, et al.
Development
. 2015 Jul;
142(15):2633-40.
PMID: 26160904
During oocyte maturation, capacity and sensitivity of Ca(2+) signaling machinery increases dramatically, preparing the metaphase II (MII)-arrested egg for fertilization. Upon sperm-egg fusion, Ca(2+) release from IP3-sensitive endoplasmic reticulum stores...
8.
Staier F, Eipel H, Matula P, Evsikov A, Kozubek M, Cremer C, et al.
Rev Sci Instrum
. 2011 Oct;
82(9):093701.
PMID: 21974588
With the development of novel fluorescence techniques, high resolution light microscopy has become a challenging technique for investigations of the three-dimensional (3D) micro-cosmos in cells and sub-cellular components. So far,...
9.
Taskesen M, Collin G, Evsikov A, Guzel A, Ozgul R, Marshall J, et al.
Hum Genet
. 2011 Aug;
131(3):407-13.
PMID: 21877133
Alström syndrome is a clinically complex disorder characterized by childhood retinal degeneration leading to blindness, sensorineural hearing loss, obesity, type 2 diabetes mellitus, cardiomyopathy, systemic fibrosis, and pulmonary, hepatic, and...
10.
Ratzan W, Evsikov A, Okamura Y, Jaffe L
J Cell Physiol
. 2011 May;
226(11):2740-6.
PMID: 21618529
Voltage-sensitive phosphatases (VSPs) are unique proteins in which membrane potential controls enzyme activity. They are comprised of the voltage sensor domain of an ion channel coupled to a lipid phosphatase...