Draft Genome Sequence of Streptomyces Clavuligerus NRRL 3585, a Producer of Diverse Secondary Metabolites

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2010 Oct 5

PMID 20889745

Citations 32

Authors

Ju Yeon Song

Haeyoung Jeong

Dong Su Yu

Michael A Fischbach

Hong-Seog Park

Jae Jong Kim

Jeong-Sun Seo

Susan E Jensen

Tae Kwang Oh

Kye Joon Lee

Jihyun F Kim

Affiliations

Soon will be listed here.

Abstract

Streptomyces clavuligerus is an important industrial strain that produces a number of antibiotics, including clavulanic acid and cephamycin C. A high-quality draft genome sequence of the S. clavuligerus NRRL 3585 strain was produced by employing a hybrid approach that involved Sanger sequencing, Roche/454 pyrosequencing, optical mapping, and partial finishing. Its genome, comprising four linear replicons, one chromosome, and four plasmids, carries numerous sets of genes involved in the biosynthesis of secondary metabolites, including a variety of antibiotics.

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