Synthesis and Antifungal Activity of Benzofuran-5-ols

Overview

Journal Bioorg Med Chem Lett

Specialty Biochemistry

Date 2010 Sep 21

PMID 20851600

Citations 6

Authors

Chung-Kyu Ryu

Ae Li Song

Jung Yoon Lee

Jung An Hong

Joo Hee Yoon

Aram Kim

Affiliations

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Abstract

Benzofuran-5-ol derivatives were synthesized and tested for in vitro antifungal activity against Candida, Aspergillus species, and Cryptococcus neoformans. Among them tested, many benzofuran-5-ols showed good antifungal activity. The results suggest that benzofuran-5-ols would be promising antifungal agents.

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