Strategies for the Synthesis of Bioactive Pyran Naphthoquinones

Overview

Journal Org Biomol Chem

Publisher Royal Society of Chemistry

Specialties Biochemistry
Chemistry

Date 2010 Sep 15

PMID 20838670

Citations 8

Authors

Vitor Francisco Ferreira

Sabrina Baptista Ferreira

Fernando de Carvalho da Silva

Affiliations

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Abstract

Taking into account the numerous reports in the literature related to pyran naphthoquinones in searching for new pharmacologically promising molecules against different therapeutic targets, this review intends to explore the synthetic methodologies for preparing these bioactive compounds.

Citing Articles

Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines-From the Synthesis to 3D-Cell Culture Effects.

da Gama Oliveira V, Muxfeldt M, Paz M, Silva Coutinho M, Dos Santos R, Diniz da Silva Ferretti G Int J Mol Sci. 2024; 25(12).

PMID: 38928197 PMC: 11203957. DOI: 10.3390/ijms25126490.

1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis.

Ribeiro R, Ferreira P, Borges A, Forezi L, de Carvalho da Silva F, Ferreira V Beilstein J Org Chem. 2022; 18:53-69.

PMID: 35047082 PMC: 8744465. DOI: 10.3762/bjoc.18.5.

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier.

Barbosa J, Nicoletti C, da Silva P, Melo T, Futuro D, Ferreira V PLoS One. 2021; 16(3):e0246811.

PMID: 33661933 PMC: 7932091. DOI: 10.1371/journal.pone.0246811.

Efficient Catalytic Oxidation of 3-Arylthio- and 3-Cyclohexylthio-lapachone Derivatives to New Sulfonyl Derivatives and Evaluation of Their Antibacterial Activities.

Cardoso M, Gomes A, Dos S Moreira C, Simoes M, Neves M, Rocha D Molecules. 2017; 22(2).

PMID: 28212345 PMC: 6155948. DOI: 10.3390/molecules22020302.

A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones.

Reis M, Campos V, Resende J, Silva F, Ferreira V Beilstein J Org Chem. 2015; 11:1235-40.

PMID: 26425181 PMC: 4578459. DOI: 10.3762/bjoc.11.137.