Amino-terminal Amino Acid Sequence of the Major Structural Polypeptides of Avian Retroviruses: Sequence Homology Between Reticuloendotheliosis Virus P30 and P30s of Mammalian Retroviruses

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 1978 Jun 1

PMID 208072

Citations 22

Authors

E Hunter

A S BHOWN

J C Bennett

Affiliations

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Abstract

The major structural polypeptides, p30 of reticuloendotheliosis virus (REV) (strain T) and p27 of avian sarcoma virus B77, have been compared with regard to amino acid composition. NH2-terminal amino acid sequence, and immunological crossreactions. The amino acid composition of the two polypeptides is distinct, and a comparison of the first 30 NH2-terminal amino acids of REV p30 with that for the first 25 of B77 p27 yields only three homologous residues. In competition radioimmunoassays the polypeptides show no crossreactivity. A comparison of the amino acid composition and NH2-terminal amino acid sequence of REV p30 with those reported for several mammalian retrovirus p30s shows remarkable similarities. Both REV and mammalian p30s contain a large number of polar residues in their amino acid composition and show approximately 40% homology in the first 30 NH2-terminal amino acids. No crossreactivity could be observed, however, in competition radioimmunoassays between Rauscher murine leukemia virus p30 and that of REV. The observations reported here suggest a close evolutionary relationship between REV and the mammalian retroviruses.

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References

Sarma P, Turner H, HUEBNER R . AN AVIAN LEUCOSIS GROUP-SPECIFIC COMPLEMENT FIXATION REACTION. APPLICATION FOR THE DETECTION AND ASSAY OF NON-CYTOPATHOGENIC LEUCOSIS VIRUSES. Virology. 1964; 23:313-21. DOI: 10.1016/0042-6822(64)90253-3. View

Brauer A, Margolies M, Haber E . The application of 0.1 M quadrol to the microsequence of proteins and the sequence of tryptic peptides. Biochemistry. 1975; 14(13):3029-35. DOI: 10.1021/bi00684a036. View

Famulari N, Buchhagen D, Klenk H, Fleissner E . Presence of murine leukemia virus envelope proteins gp70 and p15(E) in a common polyprotein of infected cells. J Virol. 1976; 20(2):501-8. PMC: 355017. DOI: 10.1128/JVI.20.2.501-508.1976. View

Bender W, Chien Y, Chattopadhyay S, Vogt P, Gardner M, Davidson N . High-molecular-weight RNAs of AKR, NZB, and wild mouse viruses and avian reticuloendotheliosis virus all have similar dimer structures. J Virol. 1978; 25(3):888-96. PMC: 525983. DOI: 10.1128/JVI.25.3.888-896.1978. View

BHOWN A, Habeerb A . Structural studies on epsilon-prototoxin of Clostridium perfringens type D. Localization of the site of tryptic scission necessary for activation to epsilon-toxin. Biochem Biophys Res Commun. 1977; 78(3):889-96. DOI: 10.1016/0006-291x(77)90506-x. View

Tarr G, Beecher J, Bell M, McKean D . Polyquarternary amines prevent peptide loss from sequenators. Anal Biochem. 1978; 84(2):622-7?0=ENG. DOI: 10.1016/0003-2697(78)90086-6. View

van ZAANE D, Bloemers H . Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus: synthesis, identification, and processing. Virology. 1976; 75(1):113-29. DOI: 10.1016/0042-6822(76)90011-8. View

Bolognesi D, Luftig R, Shaper J . Localization of RNA tumor virus polypeptides. I. Isolation of further virus substructures. Virology. 1973; 56(2):549-64. DOI: 10.1016/0042-6822(73)90057-3. View

Kang C, Temin H . Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. J Virol. 1973; 12(6):1314-24. PMC: 356773. DOI: 10.1128/JVI.12.6.1314-1324.1973. View

10.

Stephenson J, WILSNACK R, Aaronson S . Radioimmunoassay for avian C-type virus group-specific antigen: detection in normal and virus-transformed cells. J Virol. 1973; 11(6):893-9. PMC: 355197. DOI: 10.1128/JVI.11.6.893-899.1973. View

11.

Fleissner E, Tress E . Isolation of a ribonucleoprotein structure from oncornaviruses. J Virol. 1973; 12(6):1612-5. PMC: 356805. DOI: 10.1128/JVI.12.6.1612-1615.1973. View

12.

Kang C, Temin H . Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. J Virol. 1974; 14(5):1179-88. PMC: 355634. DOI: 10.1128/JVI.14.5.1179-1188.1974. View

13.

Green R, Bolognesi D . Isolation of proteins by gel filtration in 6M guanidinium chloride: application to RNA tumor viruses. Anal Biochem. 1974; 57(1):108-17. DOI: 10.1016/0003-2697(74)90057-8. View

14.

Theilen G, ZEIGEL R, TWIEHAUS M . Biological studies with RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. J Natl Cancer Inst. 1966; 37(6):731-43. View

15.

ZEIGEL R, Theilen G, TWIEHAUS M . Electron microscopic observations on RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. J Natl Cancer Inst. 1966; 37(6):709-29. View

16.

Niall H, Sauer R, Allen D . The N-terminal amino acid sequence of two avian leukosis group specific antigens. Proc Natl Acad Sci U S A. 1970; 67(4):1804-9. PMC: 283430. DOI: 10.1073/pnas.67.4.1804. View

17.

Moelling K, Gelderblom H, Pauli G, Friis R . A comparative study of the avian reticuloendotheliosis virus: relationship to murine leukemia virus and viruses of the avian sarcoma-leukosis complex. Virology. 1975; 65(2):546-57. DOI: 10.1016/0042-6822(75)90059-8. View

18.

Hunter E, Hayman M, Rongey R, Vogt P . An avian sarcoma virus mutant that is temperature sensitive for virion assembly. Virology. 1976; 69(1):35-49. DOI: 10.1016/0042-6822(76)90192-6. View

19.

Cullen S, Schwartz B . An improved method for isolation of H-2 and Ia alloantigens with immunoprecipitation induced by protein A-bearing staphylococci. J Immunol. 1976; 117(1):136-42. View

20.

Maldonado R, Bose Jr H . Group-specific antigen shared by the members of the reticuloendotheliosis virus complex. J Virol. 1976; 17(3):983-90. PMC: 515498. DOI: 10.1128/JVI.17.3.983-990.1976. View