Low Pressure Vinylation of Aryl and Vinyl Halides Via Heck-Mizoroki Reactions Using Ethylene

Overview

Journal Tetrahedron

Specialty Chemistry

Date 2010 Aug 3

PMID 20676383

Citations 6

Authors

Craig R Smith

T V RajanBabu

Affiliations

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Abstract

Aryl bromides and iodides in the presence of catalytic amounts of a palladacycle derived from acetophenone oxime and 2 equivalents of potassium acetate react with ethylene under ambient pressure (15-30 psi) to give the corresponding vinylarenes. The reactions work with both electron-deficient and electron-rich aryl compounds and tolerate wide variety of common functional groups. Vinyl bromides lead to 1,3-dienes in moderate yields.

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