» Articles » PMID: 20669289

No Increased Risk of Obstructive Sleep Apnea in Parkinson's Disease

Overview
Journal Mov Disord
Date 2010 Jul 30
PMID 20669289
Citations 39
Authors
Affiliations
Soon will be listed here.
Abstract

Pulmonary function abnormalities in Parkinson's disease (PD) might predispose patients to obstructive sleep apnea (OSA) and daytime sleepiness. Fifty-five idiopathic PD patients (mean age = 63.9) underwent three consecutive nights of in-laboratory polysomnography on their usual dopaminergic medications. Sleep apnea severity was compared to published, normative, population-based data from the Sleep Heart Health Study. Demographic and clinical data were compared in patients with and without OSA. The apnea-hyponea index (AHI) was stable across nights in PD patients, and was not different between PD patients and normative controls. Epworth Sleepiness Scale scores, Body Mass Index, and snoring did not correlate with AHI. Severity of OSA is stable across multiple nights in PD patients. Rates of OSA in PD are similar to those seen in the general population. Daytime sleepiness, snoring, and obesity may not be helpful in identifying OSA in PD.

Citing Articles

Sleep disorders in Parkinson's disease, an early and multiple problem.

Dodet P, Houot M, Leu-Semenescu S, Corvol J, Lehericy S, Mangone G NPJ Parkinsons Dis. 2024; 10(1):46.

PMID: 38424131 PMC: 10904863. DOI: 10.1038/s41531-024-00642-0.


Stroke in Parkinson's disease: a review of epidemiological studies and potential pathophysiological mechanisms.

Elfil M, Bayoumi A, Sayed A, Aladawi M, Aboutaleb P, Grieb L Acta Neurol Belg. 2023; 123(3):773-783.

PMID: 36710306 DOI: 10.1007/s13760-023-02202-4.


Validation of STOP, STOP-BANG, STOP-BAG, STOP-B28, and GOAL screening tools for identification of obstructive sleep apnea in patients with Parkinson disease.

Gomes T, Benedetti A, Lafontaine A, Kimoff R, Robinson A, Kaminska M J Clin Sleep Med. 2022; 19(1):45-54.

PMID: 36004740 PMC: 9806789. DOI: 10.5664/jcsm.10262.


Respiratory Abnormalities in Parkinson's Disease: What Do We Know from Studies in Humans and Animal Models?.

Kaczynska K, Orlowska M, Andrzejewski K Int J Mol Sci. 2022; 23(7).

PMID: 35408858 PMC: 8998219. DOI: 10.3390/ijms23073499.


Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson's Disease.

Hermann W, Schmitz-Peiffer H, Kasper E, Fauser M, Franke C, Wienecke M Front Neurosci. 2020; 14:689.

PMID: 32903712 PMC: 7438827. DOI: 10.3389/fnins.2020.00689.


References
1.
Probst A, Bloch A, Tolnay M . New insights into the pathology of Parkinson's disease: does the peripheral autonomic system become central?. Eur J Neurol. 2008; 15 Suppl 1:1-4. DOI: 10.1111/j.1468-1331.2008.02057.x. View

2.
Baumann C, Ferini-Strambi L, Waldvogel D, Werth E, Bassetti C . Parkinsonism with excessive daytime sleepiness--a narcolepsy-like disorder?. J Neurol. 2005; 252(2):139-45. DOI: 10.1007/s00415-005-0614-5. View

3.
Canning C, Alison J, Allen N, Groeller H . Parkinson's disease: an investigation of exercise capacity, respiratory function, and gait. Arch Phys Med Rehabil. 1997; 78(2):199-207. DOI: 10.1016/s0003-9993(97)90264-1. View

4.
Arnulf I, Konofal E, Merino-Andreu M, Houeto J, Mesnage V, Welter M . Parkinson's disease and sleepiness: an integral part of PD. Neurology. 2002; 58(7):1019-24. DOI: 10.1212/wnl.58.7.1019. View

5.
Diederich N, Vaillant M, Leischen M, Mancuso G, Golinval S, Nati R . Sleep apnea syndrome in Parkinson's disease. A case-control study in 49 patients. Mov Disord. 2005; 20(11):1413-8. DOI: 10.1002/mds.20624. View