Obstructive Sleep Apnea in Neurodegenerative Disorders: Current Evidence in Support of Benefit from Sleep Apnea Treatment

Overview

Journal J Clin Med

Specialty General Medicine

Date 2020 Jan 25

PMID 31973065

Citations 25

Authors

Annie C Lajoie

Anne-Louise Lafontaine

R John Kimoff

Marta Kaminska

Affiliations

Soon will be listed here.

Abstract

Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent upper airway obstruction during sleep resulting in intermittent hypoxemia and sleep fragmentation. Research has recently increasingly focused on the impact of OSA on the brain's structure and function, in particular as this relates to neurodegenerative diseases. This article reviews the links between OSA and neurodegenerative disease, focusing on Parkinson's disease, including proposed pathogenic mechanisms and current knowledge on the effects of treatment.

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