Direct Transcriptional Control of the Arabidopsis Immune Receptor FLS2 by the Ethylene-dependent Transcription Factors EIN3 and EIL1

Overview

Journal Proc Natl Acad Sci U S A

Specialty Science

Date 2010 Jul 29

PMID 20663954

Citations 114

Authors

Freddy Boutrot

Cecile Segonzac

Katherine N Chang

Hong Qiao

Joseph R Ecker

Cyril Zipfel

John P Rathjen

Affiliations

Soon will be listed here.

Abstract

In plant innate immunity, the leucine-rich repeat receptor kinase FLS2 recognizes the bacterial pathogen-associated molecular pattern (PAMP) flagellin. The molecular mechanisms underlying PAMP perception are not fully understood. Here, we reveal that the gaseous phytohormone ethylene is an integral part of PAMP-triggered immunity. Plants mutated in the key ethylene-signaling protein EIN2 are impaired in all FLS2-mediated responses, correlating with reduced FLS2 transcription and protein accumulation. The EIN3 and EIN3-like transcription factors, which depend on EIN2 activity for their accumulation, directly control FLS2 expression. Our results reveal a direct role for ethylene in regulation of an innate immune receptor.

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