Production, Modification and Bio-Applications of Magnetic Nanoparticles Gestated by Magnetotactic Bacteria

Overview

Journal Nano Res

Date 2010 Jul 16

PMID 20631916

Citations 22

Authors

Jin Xie

Kai Chen

Xiaoyuan Chen

Affiliations

Soon will be listed here.

Abstract

Magnetotactic bacteria (MTB) were first discovered by Richard P. Blakemore in 1975, and this led to the discovery of a wide collection of microorganisms with similar features i.e., the ability to internalize Fe and convert it into magnetic nanoparticles, in the form of either magnetite (Fe(3)O(4)) or greigite (Fe(3)S(4)). Studies showed that these particles are highly crystalline, monodisperse, bioengineerable and have high magnetism that is comparable to those made by advanced synthetic methods, making them candidate materials for a broad range of bio-applications. In this review article, the history of the discovery of MTB and subsequent efforts to elucidate the mechanisms behind the magnetosome formation are briefly covered. The focus is on how to utilize the knowledge gained from fundamental studies to fabricate functional MTB nanoparticles (MTB-NPs) that are capable of tackling real biomedical problems.

Citing Articles

Therapeutic Innovations in Nanomedicine: Exploring the Potential of Magnetotactic Bacteria and Bacterial Magnetosomes.

Yadav V, Pramanik S, Alghamdi S, Atwah B, Qusty N, Babalghith A Int J Nanomedicine. 2025; 20():403-444.

PMID: 39816378 PMC: 11734620. DOI: 10.2147/IJN.S462031.

Progress in affinity ligand-functionalized bacterial magnetosome nanoparticles for bio-immunomagnetic separation of HBsAg protein.

Hatami Giklou Jajan L, Hosseini S, Abolhassani M, Ghorbani M PLoS One. 2022; 17(7):e0267206.

PMID: 35877673 PMC: 9312401. DOI: 10.1371/journal.pone.0267206.

Engineering Biological Electron Transfer and Redox Pathways for Nanoparticle Synthesis.

Boedicker J, Gangan M, Naughton K, Zhao F, Gralnick J, El-Naggar M Bioelectricity. 2021; 3(2):126-135.

PMID: 34476388 PMC: 8380940. DOI: 10.1089/bioe.2021.0010.

Bioinspired Magnetic Nanochains for Medicine.

Kralj S, Marchesan S Pharmaceutics. 2021; 13(8).

PMID: 34452223 PMC: 8398308. DOI: 10.3390/pharmaceutics13081262.

Magnetic Nanodiscs-A New Promising Tool for Microsurgery of Malignant Neoplasms.

Zamay T, Prokopenko V, Zamay S, Lukyanenko K, Kolovskaya O, Orlov V Nanomaterials (Basel). 2021; 11(6).

PMID: 34072903 PMC: 8227103. DOI: 10.3390/nano11061459.

References

Bazylinski D, Frankel R, Heywood B, Mann S, King J, Donaghay P . Controlled Biomineralization of Magnetite (Fe(inf3)O(inf4)) and Greigite (Fe(inf3)S(inf4)) in a Magnetotactic Bacterium. Appl Environ Microbiol. 1995; 61(9):3232-9. PMC: 1388570. DOI: 10.1128/aem.61.9.3232-3239.1995. View

Tanaka M, Okamura Y, Arakaki A, Tanaka T, Takeyama H, Matsunaga T . Origin of magnetosome membrane: proteomic analysis of magnetosome membrane and comparison with cytoplasmic membrane. Proteomics. 2006; 6(19):5234-47. DOI: 10.1002/pmic.200500887. View

Komeili A, Li Z, Newman D, Jensen G . Magnetosomes are cell membrane invaginations organized by the actin-like protein MamK. Science. 2005; 311(5758):242-5. DOI: 10.1126/science.1123231. View

Nakamura N, Burgess J, Yagiuda K, Kudo S, Sakaguchi T, Matsunaga T . Detection and removal of Escherichia coli using fluorescein isothiocyanate conjugated monoclonal antibody immobilized on bacterial magnetic particles. Anal Chem. 1993; 65(15):2036-9. DOI: 10.1021/ac00063a018. View

Arakaki A, Nakazawa H, Nemoto M, Mori T, Matsunaga T . Formation of magnetite by bacteria and its application. J R Soc Interface. 2008; 5(26):977-99. PMC: 2475554. DOI: 10.1098/rsif.2008.0170. View

Scheffel A, Gardes A, Grunberg K, Wanner G, Schuler D . The major magnetosome proteins MamGFDC are not essential for magnetite biomineralization in Magnetospirillum gryphiswaldense but regulate the size of magnetosome crystals. J Bacteriol. 2007; 190(1):377-86. PMC: 2223754. DOI: 10.1128/JB.01371-07. View

Schuler D . Genetics and cell biology of magnetosome formation in magnetotactic bacteria. FEMS Microbiol Rev. 2008; 32(4):654-72. DOI: 10.1111/j.1574-6976.2008.00116.x. View

Matsunaga T, Togo H, Kikuchi T, Tanaka T . Production of luciferase-magnetic particle complex by recombinant Magnetospirillum sp. AMB-1. Biotechnol Bioeng. 2000; 70(6):704-9. View

Komeili A, Vali H, Beveridge T, Newman D . Magnetosome vesicles are present before magnetite formation, and MamA is required for their activation. Proc Natl Acad Sci U S A. 2004; 101(11):3839-44. PMC: 374331. DOI: 10.1073/pnas.0400391101. View

10.

Smith M, Sheehan P, Perry L, OConnor K, Csonka L, Applegate B . Quantifying the magnetic advantage in magnetotaxis. Biophys J. 2006; 91(3):1098-107. PMC: 1563769. DOI: 10.1529/biophysj.106.085167. View

11.

Weiss B, Kim S, Kirschvink J, Kopp R, Sankaran M, Kobayashi A . Magnetic tests for magnetosome chains in Martian meteorite ALH84001. Proc Natl Acad Sci U S A. 2004; 101(22):8281-4. PMC: 420385. DOI: 10.1073/pnas.0402292101. View

12.

Nakamura C, Kikuchi T, Burgess J, Matsunaga T . Iron-regulated expression and membrane localization of the magA protein in Magnetospirillum sp. strain AMB-1. J Biochem. 1995; 118(1):23-7. DOI: 10.1093/oxfordjournals.jbchem.a124884. View

13.

Gorby Y, Beveridge T, Blakemore R . Characterization of the bacterial magnetosome membrane. J Bacteriol. 1988; 170(2):834-41. PMC: 210730. DOI: 10.1128/jb.170.2.834-841.1988. View

14.

Bazylinski D, Frankel R . Magnetosome formation in prokaryotes. Nat Rev Microbiol. 2004; 2(3):217-30. DOI: 10.1038/nrmicro842. View

15.

Yoza B, Arakaki A, Matsunaga T . DNA extraction using bacterial magnetic particles modified with hyperbranched polyamidoamine dendrimer. J Biotechnol. 2003; 101(3):219-28. DOI: 10.1016/s0168-1656(02)00342-5. View

16.

Xia M, Wei J, Lei Y, Ying L . A novel ferric reductase purified from Magnetospirillum gryphiswaldense MSR-1. Curr Microbiol. 2007; 55(1):71-5. DOI: 10.1007/s00284-007-0023-3. View

17.

Schuler D, Frankel R . Bacterial magnetosomes: microbiology, biomineralization and biotechnological applications. Appl Microbiol Biotechnol. 1999; 52(4):464-73. DOI: 10.1007/s002530051547. View

18.

Heyen U, Schuler D . Growth and magnetosome formation by microaerophilic Magnetospirillum strains in an oxygen-controlled fermentor. Appl Microbiol Biotechnol. 2003; 61(5-6):536-44. DOI: 10.1007/s00253-002-1219-x. View

19.

Richter M, Kube M, Bazylinski D, Lombardot T, Glockner F, Reinhardt R . Comparative genome analysis of four magnetotactic bacteria reveals a complex set of group-specific genes implicated in magnetosome biomineralization and function. J Bacteriol. 2007; 189(13):4899-910. PMC: 1913459. DOI: 10.1128/JB.00119-07. View

20.

Arakaki A, Webb J, Matsunaga T . A novel protein tightly bound to bacterial magnetic particles in Magnetospirillum magneticum strain AMB-1. J Biol Chem. 2002; 278(10):8745-50. DOI: 10.1074/jbc.M211729200. View