Nutritional Therapy for the Treatment of Pediatric Crohn's Disease

Overview

Journal Expert Rev Clin Immunol

Specialty Allergy & Immunology

Date 2010 Jul 3

PMID 20594139

Citations 8

Authors

Anthony R Otley

Richard K Russell

Andew S Day

Affiliations

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Abstract

Crohn's disease and ulcerative colitis are lifelong conditions with particular effects upon nutrition, especially in children and adolescents. Various therapies are available for these conditions but there remains no cure. Over the last decades, exclusive enteral nutrition (EEN) has been demonstrated to have efficacy in the induction of remission, along with numerous other nutritional and inflammatory benefits. This article reviews the benefits and outcomes associated with EEN in Crohn's disease. The potential mechanisms of this therapy are highlighted, along with factors that are barriers to the wider use of EEN.

Citing Articles

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Global attitudes on and the status of enteral nutrition therapy for pediatric inflammatory bowel disease.

Luo J, Xie Y, Wu M, Zhao J, Hu L Front Med (Lausanne). 2022; 9:1036793.

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Exclusive Enteral Nutrition Induces Remission in Pediatric Crohn's Disease via Modulation of the Gut Microbiota.

Gong D, Yu X, Wang L, Kong L, Gong X, Dong Q Biomed Res Int. 2017; 2017:8102589.

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The Impact of Exclusive Enteral Nutrition (EEN) on the Gut Microbiome in Crohn's Disease: A Review.

MacLellan A, Moore-Connors J, Grant S, Cahill L, Langille M, Van Limbergen J Nutrients. 2017; 9(5).

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The major pathway by which polymeric formula reduces inflammation in intestinal epithelial cells: a microarray-based analysis.

Nahidi L, Corley S, Wilkins M, Wei J, Alhagamhmad M, Day A Genes Nutr. 2015; 10(5):479.

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