Escape from X Inactivation in Mice and Humans

Overview

Journal Genome Biol

Specialties Biology
Genetics

Date 2010 Jun 25

PMID 20573260

Citations 109

Authors

Joel B Berletch

Fan Yang

Christine M Disteche

Affiliations

Soon will be listed here.

Abstract

A subset of X-linked genes escapes silencing by X inactivation and is expressed from both X chromosomes in mammalian females. Species-specific differences in the identity of these genes have recently been discovered, suggesting a role in the evolution of sex differences. Chromatin analyses have aimed to discover how genes remain expressed within a repressive environment.

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