MassSieve: Panning MS/MS Peptide Data for Proteins

Overview

Journal Proteomics

Date 2010 Jun 22

PMID 20564260

Citations 28

Authors

Douglas J Slotta

Melinda A McFarland

Sanford P Markey

Affiliations

Soon will be listed here.

Abstract

We present MassSieve, a Java-based platform for visualization and parsimony analysis of single and comparative LC-MS/MS database search engine results. The success of mass spectrometric peptide sequence assignment algorithms has led to the need for a tool to merge and evaluate the increasing data set sizes that result from LC-MS/MS-based shotgun proteomic experiments. MassSieve supports reports from multiple search engines with differing search characteristics, which can increase peptide sequence coverage and/or identify conflicting or ambiguous spectral assignments.

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