Do Ion Levels in Hip Resurfacing Differ from Metal-on-metal THA at Midterm?
Overview
Authors
Affiliations
Background: Metal-on-metal Birmingham hip resurfacing (MOM-BHR) is an alternative to metal-on-metal total hip arthroplasty (MOM-THA), especially for young and/or active patients. However, wear resulting in increased serum ion levels is a concern.
Questions/purposes: We asked whether (1) serum chromium (Cr), cobalt (Co), and molybdenum (Mo) concentrations would differ between patients with either MOM-BHR or MOM-THA at 5 years, (2) confounding factors such as gender would influence ion levels; and (3) ion levels would differ at 2 and 5 years for each implant type.
Patients And Methods: Ions were measured in two groups with either MOM-BHR (n = 20) or MOM-THA (n = 35) and a mean 5-year followup, and two groups with either MOM-BHR (n = 15) or MOM-THA (n = 25) and a mean 2-year followup. Forty-eight healthy blood donors were recruited for reference values.
Results: At 5 years, there were no differences in ion levels between patients with MOM-BHR or MOM-THA. Gender was a confounding factor, and in the MOM-BHR group at 5 years, Cr concentrations were greater in females compared with those of males. Mean ion levels were similar in patients with 2 and 5 years of followup for each implant type. Ion levels in patients were sevenfold to 10-fold higher than in controls.
Conclusions: As the metal ion concentrations in the serum at 5 years were in the range reported in the literature, we do not believe concerns regarding excessive metal ion levels after MOM-BHR are justified.
Level Of Evidence: Level III, therapeutic study. See the Guidelines for Authors for a complete description of level of evidence.
Wu K, Pang L, Su P, Lv C Front Aging Neurosci. 2025; 16:1505645.
PMID: 39759400 PMC: 11695404. DOI: 10.3389/fnagi.2024.1505645.
Qi X, Liu J, Liu W, Qiao X, Fu J, Gao J Sci Rep. 2024; 14(1):17111.
PMID: 39048613 PMC: 11269588. DOI: 10.1038/s41598-024-68049-8.
Pozzuoli A, Berizzi A, Crimi A, Belluzzi E, Frigo A, De Conti G Diagnostics (Basel). 2020; 10(11).
PMID: 33198180 PMC: 7698262. DOI: 10.3390/diagnostics10110941.
Changes in serum chromium levels over 12 years after Metasul metal-on-metal total hip arthroplasty.
Maezawa K, Nozawa M, Yuasa T, Sugimoto M, Kaneko K J Orthop. 2018; 15(1):201-204.
PMID: 29657468 PMC: 5895913. DOI: 10.1016/j.jor.2018.01.047.
Smeekes C, Schouten B, Nix M, Ongkiehong B, Wolterbeek R, van der Wal B Skeletal Radiol. 2018; 47(8):1099-1109.
PMID: 29388037 PMC: 6003970. DOI: 10.1007/s00256-018-2873-0.