IL-1 and Allergy

Overview

Journal Allergol Int

Publisher Elsevier

Specialty Allergy & Immunology

Date 2010 Apr 24

PMID 20414049

Citations 19

Authors

Aya Nambu

Susumu Nakae

Affiliations

Soon will be listed here.

Abstract

IL-1 is a well-characterized proinflammatory cytokine that is involved in host defense and autoimmune diseases. IL-1 can promote activation of T cells, including Th1 cells, Th2 cells and Th17 cells, and B cells, suggesting that IL-1 may contribute to the development of various types of T-cell-mediated diseases. This report reviews and discusses the role of IL-1 in the pathogenesis of allergic diseases based on studies using IL-1-related gene-deficient mice.

Citing Articles

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Co-Activation of Human Whole Blood Cells with Lipopolysaccharides and an Allergen.

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IL-1 and Allergy: Focusing on Its Role in Allergic Rhinitis.

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Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells.

Ritvo P, Klatzmann D Front Immunol. 2019; 10:250.

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