Functional Evaluation of Hidden Figures Object Analysis in Children with Autistic Disorder

Overview

Journal J Autism Dev Disord

Publisher Springer

Date 2010 Apr 23

PMID 20411412

Citations 6

Authors

Krisztina L Malisza

Christine Clancy

Deborah Shiloff

Derek Foreman

Jeanette Holden

Cheryl Jones

K Paulson

Randy Summers

C T Yu

Albert E Chudley

Affiliations

Soon will be listed here.

Abstract

Functional magnetic resonance imaging (fMRI) during performance of a hidden figures task (HFT) was used to compare differences in brain function in children diagnosed with autism disorder (AD) compared to children with attention-deficit/hyperactivity disorder (ADHD) and typical controls (TC). Overall greater functional MRI activity was observed in the two control groups compared to children with AD. Laterality differences were also evident, with AD subjects preferentially showing activity in the right medial temporal region while controls tended to activate the left medial temporal cortex. Reduced fMRI activity was observed in the parietal, ventral-temporal and hippocampal regions in the AD group, suggesting differences in the way that children with AD process the HFT.

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