Host Responses to Candida Albicans: Th17 Cells and Mucosal Candidiasis

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2010 Apr 13

PMID 20381638

Citations 71

Authors

Heather R Conti

Sarah L Gaffen

Affiliations

Soon will be listed here.

Abstract

Candida albicans causes mucosal and disseminated candidiasis, which represent serious problems for the rapidly expanding immunocompromised population. Until recently, Th1-mediated immunity was thought to confer the primary protection, particularly for oral candidiasis. However, emerging data indicate that the newly-defined Th17 compartment appears to play the predominant role in mucosal candidiasis.

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