A Common Progenitor for Retinal Astrocytes and Oligodendrocytes

Overview

Journal J Neurosci

Specialty Neurology

Date 2010 Apr 8

PMID 20371817

Citations 24

Authors

Santiago B Rompani

Constance L Cepko

Affiliations

Soon will be listed here.

Abstract

Developing neural tissue undergoes a period of neurogenesis followed by a period of gliogenesis. The lineage relationships among glial cell types have not been defined for most areas of the nervous system. Here we use retroviruses to label clones of glial cells in the chick retina. We found that almost every clone had both astrocytes and oligodendrocytes. In addition, we discovered a novel glial cell type, with features intermediate between those of astrocytes and oligodendrocytes, which we have named the diacyte. Diacytes also share a progenitor cell with both astrocytes and oligodendrocytes.

Citing Articles

Chromatin access regulates the formation of Müller glia-derived progenitor cells in the retina.

Campbell W, El-Hodiri H, Torres D, Hawthorn E, Kelly L, Volkov L Glia. 2023; 71(7):1729-1754.

PMID: 36971459 PMC: 11335016. DOI: 10.1002/glia.24366.

Fatty acid-binding proteins and fatty acid synthase influence glial reactivity and promote the formation of Müller glia-derived progenitor cells in the chick retina.

Campbell W, Tangeman A, El-Hodiri H, Hawthorn E, Hathoot M, Blum S Development. 2022; 149(5).

PMID: 35132991 PMC: 8959147. DOI: 10.1242/dev.200127.

Nuclear Factor I in neurons, glia and during the formation of Müller glia-derived progenitor cells in avian, porcine and primate retinas.

El-Hodiri H, Campbell W, Kelly L, Hawthorn E, Schwartz M, Jalligampala A J Comp Neurol. 2021; 530(8):1213-1230.

PMID: 34729776 PMC: 8969175. DOI: 10.1002/cne.25270.

A cell atlas of the chick retina based on single-cell transcriptomics.

Yamagata M, Yan W, Sanes J Elife. 2021; 10.

PMID: 33393903 PMC: 7837701. DOI: 10.7554/eLife.63907.

NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina.

Palazzo I, Deistler K, Hoang T, Blackshaw S, Fischer A Development. 2020; 147(10).

PMID: 32291273 PMC: 7325431. DOI: 10.1242/dev.183418.

References

Naldini L, Blomer U, Gage F, Trono D, Verma I . Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. Proc Natl Acad Sci U S A. 1996; 93(21):11382-8. PMC: 38066. DOI: 10.1073/pnas.93.21.11382. View

Ye P, Bagnell R, DErcole A . Mouse NG2+ oligodendrocyte precursors express mRNA for proteolipid protein but not its DM-20 variant: a study of laser microdissection-captured NG2+ cells. J Neurosci. 2003; 23(11):4401-5. PMC: 6740786. View

Fu H, Qiu M . Migration and differentiation of Nkx-2.2+ oligodendrocyte progenitors in embryonic chicken retina. Brain Res Dev Brain Res. 2001; 129(1):115-8. DOI: 10.1016/s0165-3806(01)00178-x. View

Raff M, Miller R, Noble M . A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature. 1983; 303(5916):390-6. DOI: 10.1038/303390a0. View

Groves A, Barnett S, Franklin R, Crang A, Mayer M, Blakemore W . Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells. Nature. 1993; 362(6419):453-5. DOI: 10.1038/362453a0. View

Kim D, Park S, Jeon G, Seo J, Golden J, Cho S . The multiple dorsoventral origins and migratory pathway of tectal oligodendrocytes in the developing chick. Brain Res. 2006; 1076(1):16-24. DOI: 10.1016/j.brainres.2006.01.010. View

Fekete D, Cepko C . Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo. Mol Cell Biol. 1993; 13(4):2604-13. PMC: 359596. DOI: 10.1128/mcb.13.4.2604-2613.1993. View

Fogarty M, Richardson W, Kessaris N . A subset of oligodendrocytes generated from radial glia in the dorsal spinal cord. Development. 2005; 132(8):1951-9. DOI: 10.1242/dev.01777. View

Rompani S, Cepko C . Retinal progenitor cells can produce restricted subsets of horizontal cells. Proc Natl Acad Sci U S A. 2007; 105(1):192-7. PMC: 2224184. DOI: 10.1073/pnas.0709979104. View

10.

Cai J, Qi Y, Hu X, Tan M, Liu Z, Zhang J . Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling. Neuron. 2005; 45(1):41-53. DOI: 10.1016/j.neuron.2004.12.028. View

11.

Seo J, Haam Y, Park S, Kim D, Jeon G, Lee C . Oligodendroglia in the avian retina: immunocytochemical demonstration in the adult bird. J Neurosci Res. 2001; 65(2):173-83. DOI: 10.1002/jnr.1140. View

12.

Dutting D, Gierer A, Hansmann G . Self-renewal of stem cells and differentiation of nerve cells in the developing chick retina. Brain Res. 1983; 312(1):21-32. DOI: 10.1016/0165-3806(83)90117-7. View

13.

Espinosa de Los Monteros A, Zhang M, de Vellis J . O2A progenitor cells transplanted into the neonatal rat brain develop into oligodendrocytes but not astrocytes. Proc Natl Acad Sci U S A. 1993; 90(1):50-4. PMC: 45597. DOI: 10.1073/pnas.90.1.50. View

14.

Rivers L, Young K, Rizzi M, Jamen F, Psachoulia K, Wade A . PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice. Nat Neurosci. 2008; 11(12):1392-401. PMC: 3842596. DOI: 10.1038/nn.2220. View

15.

Ono K, Tsumori T, Kishi T, Yokota S, Yasui Y . Developmental appearance of oligodendrocytes in the embryonic chick retina. J Comp Neurol. 1998; 398(3):309-22. View

16.

Temple S, Raff M . Differentiation of a bipotential glial progenitor cell in a single cell microculture. Nature. 1985; 313(5999):223-5. DOI: 10.1038/313223a0. View

17.

Chan-Ling T, Chu Y, Baxter L, Weible Ii M, Hughes S . In vivo characterization of astrocyte precursor cells (APCs) and astrocytes in developing rat retinae: differentiation, proliferation, and apoptosis. Glia. 2008; 57(1):39-53. DOI: 10.1002/glia.20733. View

18.

Mishima H, Fujita H . Studies on the cytodifferentiation of the neuroblasts and visual cells in the chick embryo retina, using the electron-microscopic autoradiography of 3H-thymidine. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978; 206(1):1-10. DOI: 10.1007/BF00411331. View

19.

Kessaris N, Fogarty M, Iannarelli P, Grist M, Wegner M, Richardson W . Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. Nat Neurosci. 2006; 9(2):173-9. PMC: 6328015. DOI: 10.1038/nn1620. View

20.

Raff M, Abney E, Miller R . Two glial cell lineages diverge prenatally in rat optic nerve. Dev Biol. 1984; 106(1):53-60. DOI: 10.1016/0012-1606(84)90060-5. View