Primary Pancreatic Lymphoma in Korea--a Single Center Experience

Overview

Journal J Korean Med Sci

Specialty General Medicine

Date 2010 Apr 2

PMID 20357994

Citations 8

Authors

Won Jae Yoon

Yong Bum Yoon

Youn Joo Kim

Ji Kon Ryu

Yong-Tae Kim

Affiliations

Soon will be listed here.

Abstract

The aim of this study was to report a single center experience of primary pancreatic lymphoma (PPL) in Korea. We analyzed the clinicopathological data from four PPL patients (three male, median age 36 yr) diagnosed from 1997 to 2007 at Seoul National University Hospital. The diagnoses were: diffuse large B cell lymphoma (n=2), Ki-1 (+) anaplastic large cell lymphoma (n=1), and Burkitt lymphoma (n=1). Presenting symptoms and signs were: abdominal pain (n=4), pancreatitis (n=2), weight loss (n=2) and abdominal mass (n=1). No patient underwent surgery. The Ann Arbor stages of the patients were: IEA (n=1), IIEA (n=1), and IVEB (n=2). Two patients underwent treatment. The stage IEA patient underwent chemotherapy and radiation therapy that resulted in a complete remission. The stage IVEB patient who underwent chemotherapy relapsed. This patient underwent subsequent peripheral blood stem cell transplantation and is alive at 30 months. Two patients (stages IVEB and IIEA) without treatment died at 0.8 and 7.0 months, respectively. For PPL patients, chemotherapy-based treatment, and addition of radiation therapy, if possible, may offer good prognosis.

Citing Articles

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Sporadic Burkitt Lymphoma Presenting with Middle Cranial Fossa Masses with Sphenoid Bony Invasion and Acute Pancreatitis in a Child.

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[Pancreatitis as the initial manifestation and abdominal lymph node enlargement in a boy].

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Primary Pancreatic Burkitt's Lymphoma: A Case Report and Review of the Literature.

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