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Decoding the Function of Nuclear Long Non-coding RNAs

Overview
Publisher Elsevier
Specialty Cell Biology
Date 2010 Apr 2
PMID 20356723
Citations 118
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Abstract

Long non-coding RNAs (lncRNAs) are mRNA-like, non-protein-coding RNAs that are pervasively transcribed throughout eukaryotic genomes. Rather than silently accumulating in the nucleus, many of these are now known or suspected to play important roles in nuclear architecture or in the regulation of gene expression. In this review, we highlight some recent progress in how lncRNAs regulate these important nuclear processes at the molecular level.

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