Nucleobase-containing Peptides: an Overview of Their Characteristic Features and Applications

Overview

Journal Amino Acids

Specialty Biochemistry

Date 2010 Mar 30

PMID 20349320

Citations 14

Authors

Giovanni N Roviello

Ettore Benedetti

Carlo Pedone

Enrico M Bucci

Affiliations

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Abstract

Reports on nucleobase-containing chiral peptides (both natural and artificial) and achiral pseudopeptides are reviewed. Their synthesis, structural features, DNA and RNA-binding ability, as well as some other interesting applications which make them promising diagnostic/therapeutic agents of great importance in many areas of biology and therapy are taken into critical consideration.

Citing Articles

Dancing with Nucleobases: Unveiling the Self-Assembly Properties of DNA and RNA Base-Containing Molecules for Gel Formation.

Scognamiglio P, Vicidomini C, Roviello G Gels. 2024; 10(1).

PMID: 38247739 PMC: 10815473. DOI: 10.3390/gels10010016.

Willardiine and Its Synthetic Analogues: Biological Aspects and Implications in Peptide Chemistry of This Nucleobase Amino Acid.

Palumbo R, Omodei D, Vicidomini C, Roviello G Pharmaceuticals (Basel). 2022; 15(10).

PMID: 36297355 PMC: 9611319. DOI: 10.3390/ph15101243.

Genomics-Guided Efficient Identification of 2,5-Diketopiperazine Derivatives from Actinobacteria.

Liu J, Li S Chembiochem. 2022; 24(3):e202200502.

PMID: 36098493 PMC: 10092475. DOI: 10.1002/cbic.202200502.

From Prebiotic Chemistry to Supramolecular Biomedical Materials: Exploring the Properties of Self-Assembling Nucleobase-Containing Peptides.

Scognamiglio P, Platella C, Napolitano E, Musumeci D, Roviello G Molecules. 2021; 26(12).

PMID: 34200901 PMC: 8230524. DOI: 10.3390/molecules26123558.

Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other Coronaviruses.

Borbone N, Piccialli G, Roviello G, Oliviero G Molecules. 2021; 26(4).

PMID: 33668428 PMC: 7918729. DOI: 10.3390/molecules26040986.